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Targeting CISH enhances natural cytotoxicity receptor signaling and reduces NK cell exhaustion to improve solid tumor immunity.
Bernard PL, Delconte R, Pastor S, Laletin V, Costa Da Silva C, Goubard A, Josselin E, Castellano R, Krug A, Vernerey J, Devillier R, Olive D, Verhoeyen E, Vivier E, Huntington ND, Nunes J, Guittard G. Bernard PL, et al. Among authors: krug a. J Immunother Cancer. 2022 May;10(5):e004244. doi: 10.1136/jitc-2021-004244. J Immunother Cancer. 2022. PMID: 35589278 Free PMC article.
Dependence on mitochondrial respiration of malignant T cells reveals a new therapeutic target for angioimmunoblastic T-cell lymphoma.
Krug A, Mhaidly R, Tosolini M, Mondragon L, Tari G, Turtos AM, Paul-Bellon R, Asnafi V, Marchetti S, Di Mascio L, Travert M, Bost F, Bachy E, Argüello RJ, Fournié JJ, Gaulard P, Lemonnier F, Ricci JE, Verhoeyen E. Krug A, et al. Cell Death Discov. 2024 Jun 19;10(1):292. doi: 10.1038/s41420-024-02061-9. Cell Death Discov. 2024. PMID: 38897995 Free PMC article.
Baboon Envelope Pseudotyped "Nanoblades" Carrying Cas9/gRNA Complexes Allow Efficient Genome Editing in Human T, B, and CD34+ Cells and Knock-in of AAV6-Encoded Donor DNA in CD34+ Cells.
Gutierrez-Guerrero A, Abrey Recalde MJ, Mangeot PE, Costa C, Bernadin O, Périan S, Fusil F, Froment G, Martinez-Turtos A, Krug A, Martin F, Benabdellah K, Ricci EP, Giovannozzi S, Gijsbers R, Ayuso E, Cosset FL, Verhoeyen E. Gutierrez-Guerrero A, et al. Among authors: krug a. Front Genome Ed. 2021 Feb 9;3:604371. doi: 10.3389/fgeed.2021.604371. eCollection 2021. Front Genome Ed. 2021. PMID: 34713246 Free PMC article.
463 results