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Caffeine relaxes smooth muscle through actin depolymerization.
Tazzeo T, Bates G, Roman HN, Lauzon AM, Khasnis MD, Eto M, Janssen LJ. Tazzeo T, et al. Among authors: khasnis md. Am J Physiol Lung Cell Mol Physiol. 2012 Aug 15;303(4):L334-42. doi: 10.1152/ajplung.00103.2012. Epub 2012 Jun 8. Am J Physiol Lung Cell Mol Physiol. 2012. PMID: 22683573 Free PMC article.