In uveal melanoma Gα-protein GNA11 mutations convey a shorter disease-specific survival and are more strongly associated with loss of BAP1 and chromosomal alterations than Gα-protein GNAQ mutations.
Piaggio F, Croce M, Reggiani F, Monti P, Bernardi C, Ambrosio M, Banelli B, Dogrusöz M, Jockers R, Bordo D, Puzone R, Viaggi S, Coviello D, Lanza FB, Bartolucci M, Petretto A, Mosci C, Gangemi R, van der Velden PA, Jager MJ, Pfeffer U, Amaro A.
Piaggio F, et al. Among authors: monti p.
Eur J Cancer. 2022 Jul;170:27-41. doi: 10.1016/j.ejca.2022.04.013. Epub 2022 May 14.
Eur J Cancer. 2022.
PMID: 35580369