Matter H - Search Results

1

Molecular basis for inhibiting human glucose transporters by exofacial inhibitors.

Wang N, Zhang S, Yuan Y, Xu H, Defossa E, Matter H, Besenius M, Derdau V, Dreyer M, Halland N, He KH, Petry S, Podeschwa M, Tennagels N, Jiang X, Yan N. Wang N, et al. Among authors: matter h. Nat Commun. 2022 May 12;13(1):2632. doi: 10.1038/s41467-022-30326-3. Nat Commun. 2022. PMID: 35552392 Free PMC article.

2

Design and quantitative structure-activity relationship of 3-amidinobenzyl-1H-indole-2-carboxamides as potent, nonchiral, and selective inhibitors of blood coagulation factor Xa.

Matter H, Defossa E, Heinelt U, Blohm PM, Schneider D, Müller A, Herok S, Schreuder H, Liesum A, Brachvogel V, Lönze P, Walser A, Al-Obeidi F, Wildgoose P. Matter H, et al. J Med Chem. 2002 Jun 20;45(13):2749-69. doi: 10.1021/jm0111346. J Med Chem. 2002. PMID: 12061878

3

Identification and Characterization of a Single High-Affinity Fatty Acid Binding Site in Human Serum Albumin.

Wenskowsky L, Schreuder H, Derdau V, Matter H, Volkmar J, Nazaré M, Opatz T, Petry S. Wenskowsky L, et al. Among authors: matter h. Angew Chem Int Ed Engl. 2018 Jan 22;57(4):1044-1048. doi: 10.1002/anie.201710437. Epub 2017 Dec 27. Angew Chem Int Ed Engl. 2018. PMID: 29193545

4

Design, Synthesis, and Pharmacological Evaluation of Potent Positive Allosteric Modulators of the Glucagon-like Peptide-1 Receptor (GLP-1R).

Méndez M, Matter H, Defossa E, Kurz M, Lebreton S, Li Z, Lohmann M, Löhn M, Mors H, Podeschwa M, Rackelmann N, Riedel J, Safar P, Thorpe DS, Schäfer M, Weitz D, Breitschopf K. Méndez M, et al. Among authors: matter h. J Med Chem. 2020 Mar 12;63(5):2292-2307. doi: 10.1021/acs.jmedchem.9b01071. Epub 2019 Oct 23. J Med Chem. 2020. PMID: 31596080

5

Resolving Binding Events on the Multifunctional Human Serum Albumin.

Wenskowsky L, Wagner M, Reusch J, Schreuder H, Matter H, Opatz T, Petry SM. Wenskowsky L, et al. Among authors: matter h. ChemMedChem. 2020 May 6;15(9):738-743. doi: 10.1002/cmdc.202000069. Epub 2020 Mar 19. ChemMedChem. 2020. PMID: 32162429 Free PMC article.

6

Probing the subpockets of factor Xa reveals two binding modes for inhibitors based on a 2-carboxyindole scaffold: a study combining structure-activity relationship and X-ray crystallography.

Nazaré M, Will DW, Matter H, Schreuder H, Ritter K, Urmann M, Essrich M, Bauer A, Wagner M, Czech J, Lorenz M, Laux V, Wehner V. Nazaré M, et al. Among authors: matter h. J Med Chem. 2005 Jul 14;48(14):4511-25. doi: 10.1021/jm0490540. J Med Chem. 2005. PMID: 15999990

7

Discovery and Optimization of 1-Phenoxy-2-aminoindanes as Potent, Selective, and Orally Bioavailable Inhibitors of the Na⁺/H⁺ Exchanger Type 3 (NHE3).

Rackelmann N, Matter H, Englert H, Follmann M, Maier T, Weston J, Arndt P, Heyse W, Mertsch K, Wirth K, Bialy L. Rackelmann N, et al. Among authors: matter h. J Med Chem. 2016 Oct 13;59(19):8812-8829. doi: 10.1021/acs.jmedchem.6b00624. Epub 2016 Sep 22. J Med Chem. 2016. PMID: 27606885

8

Selecting optimally diverse compounds from structure databases: a validation study of two-dimensional and three-dimensional molecular descriptors.

Matter H. Matter H. J Med Chem. 1997 Apr 11;40(8):1219-29. doi: 10.1021/jm960352+. J Med Chem. 1997. PMID: 9111296

9

Random or rational design? Evaluation of diverse compound subsets from chemical structure databases.

Pötter T, Matter H. Pötter T, et al. Among authors: matter h. J Med Chem. 1998 Feb 12;41(4):478-88. doi: 10.1021/jm9700878. J Med Chem. 1998. PMID: 9484498

10

Quantitative structure-activity relationship of human neutrophil collagenase (MMP-8) inhibitors using comparative molecular field analysis and X-ray structure analysis.

Matter H, Schwab W, Barbier D, Billen G, Haase B, Neises B, Schudok M, Thorwart W, Schreuder H, Brachvogel V, Lönze P, Weithmann KU. Matter H, et al. J Med Chem. 1999 Jun 3;42(11):1908-20. doi: 10.1021/jm980631s. J Med Chem. 1999. PMID: 10354399

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