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Influenza virus replication in cardiomyocytes drives heart dysfunction and fibrosis.
Sci Adv. 2022 May 13;8(19):eabm5371. doi: 10.1126/sciadv.abm5371. Epub 2022 May 11.
Sci Adv. 2022.
PMID: 35544568
Free PMC article.
Caspase-4/11 exacerbates disease severity in SARS-CoV-2 infection by promoting inflammation and immunothrombosis.
Eltobgy MM, Zani A, Kenney AD, Estfanous S, Kim E, Badr A, Carafice C, Daily K, Whitham O, Pietrzak M, Webb A, Kawahara J, Eddy AC, Denz P, Lu M, Kc M, Peeples ME, Li J, Zhu J, Que J, Robinson R, Rosas Mejia O, Rayner RE, Hall-Stoodley L, Seveau S, Gavrilin MA, Zhang X, Thomas J, Kohlmeier JE, Suthar MS, Oltz E, Tedeschi A, Robledo-Avila FH, Partida-Sanchez S, Hemann EA, Abdelrazik E, Forero A, Nimjee SM, Boyaka PN, Cormet-Boyaka E, Yount JS, Amer AO.
Eltobgy MM, et al.
Proc Natl Acad Sci U S A. 2022 May 24;119(21):e2202012119. doi: 10.1073/pnas.2202012119. Epub 2022 May 19.
Proc Natl Acad Sci U S A. 2022.
PMID: 35588457
Free PMC article.
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Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer.
Alam A, Levanduski E, Denz P, Villavicencio HS, Bhatta M, Alhorebi L, Zhang Y, Gomez EC, Morreale B, Senchanthisai S, Li J, Turowski SG, Sexton S, Sait SJ, Singh PK, Wang J, Maitra A, Kalinski P, DePinho RA, Wang H, Liao W, Abrams SI, Segal BH, Dey P.
Alam A, et al.
Cancer Cell. 2022 Feb 14;40(2):153-167.e11. doi: 10.1016/j.ccell.2022.01.003. Epub 2022 Feb 3.
Cancer Cell. 2022.
PMID: 35120601
Free PMC article.
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Oncogenic KRAS-Driven Metabolic Reprogramming in Pancreatic Cancer Cells Utilizes Cytokines from the Tumor Microenvironment.
Dey P, Li J, Zhang J, Chaurasiya S, Strom A, Wang H, Liao WT, Cavallaro F, Denz P, Bernard V, Yen EY, Genovese G, Gulhati P, Liu J, Chakravarti D, Deng P, Zhang T, Carbone F, Chang Q, Ying H, Shang X, Spring DJ, Ghosh B, Putluri N, Maitra A, Wang YA, DePinho RA.
Dey P, et al.
Cancer Discov. 2020 Apr;10(4):608-625. doi: 10.1158/2159-8290.CD-19-0297. Epub 2020 Feb 11.
Cancer Discov. 2020.
PMID: 32046984
Free PMC article.
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IFN-λ uniquely promotes CD8 T cell immunity against SARS-CoV-2 relative to type I IFN.
Solstad AD, Denz PJ, Kenney AD, Mahfooz NS, Speaks S, Gong Q, Robinson RT, Long ME, Forero A, Yount JS, Hemann EA.
Solstad AD, et al. Among authors: denz pj.
JCI Insight. 2024 May 21;9(13):e171830. doi: 10.1172/jci.insight.171830.
JCI Insight. 2024.
PMID: 38973611
Free PMC article.
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Gasdermin D promotes influenza virus-induced mortality through neutrophil amplification of inflammation.
Speaks S, McFadden MI, Zani A, Solstad A, Leumi S, Roettger JE, Kenney AD, Bone H, Zhang L, Denz PJ, Eddy AC, Amer AO, Robinson RT, Cai C, Ma J, Hemann EA, Forero A, Yount JS.
Speaks S, et al. Among authors: denz pj.
Nat Commun. 2024 Mar 29;15(1):2751. doi: 10.1038/s41467-024-47067-0.
Nat Commun. 2024.
PMID: 38553499
Free PMC article.
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Innate immune control of influenza virus interspecies adaptation.
Denz PJ, Speaks S, Kenney AD, Eddy AC, Papa JL, Roettger J, Scace SC, Hemann EA, Forero A, Webby RJ, Bowman AS, Yount JS.
Denz PJ, et al.
bioRxiv [Preprint]. 2023 Aug 23:2023.08.23.554491. doi: 10.1101/2023.08.23.554491.
bioRxiv. 2023.
PMID: 37662304
Free PMC article.
Preprint.
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