Tian XY - Search Results

1

A novel aromatic amide derivative SY-65 co-targeted tubulin and histone deacetylase 1 with potent anticancer activity in vitro and in vivo.

Li YR, Liu FF, Liu WB, Zhang YF, Tian XY, Fu XJ, Xu Y, Song J, Zhang SY. Li YR, et al. Among authors: tian xy. Biochem Pharmacol. 2022 Jul;201:115070. doi: 10.1016/j.bcp.2022.115070. Epub 2022 May 5. Biochem Pharmacol. 2022. PMID: 35526597

2

Drug Discovery Targeting Focal Adhesion Kinase (FAK) as a Promising Cancer Therapy.

Pang XJ, Liu XJ, Liu Y, Liu WB, Li YR, Yu GX, Tian XY, Zhang YB, Song J, Jin CY, Zhang SY. Pang XJ, et al. Among authors: tian xy. Molecules. 2021 Jul 13;26(14):4250. doi: 10.3390/molecules26144250. Molecules. 2021. PMID: 34299525 Free PMC article. Review.

3

Design, Synthesis, and Anticancer Activity Studies of Novel Quinoline-Chalcone Derivatives.

Guan YF, Liu XJ, Yuan XY, Liu WB, Li YR, Yu GX, Tian XY, Zhang YB, Song J, Li W, Zhang SY. Guan YF, et al. Among authors: tian xy. Molecules. 2021 Aug 13;26(16):4899. doi: 10.3390/molecules26164899. Molecules. 2021. PMID: 34443487 Free PMC article.

4

Discovery of 1,2,4-triazine dithiocarbamate derivatives as NEDDylation agonists to inhibit gastric cancers.

Song J, Liu Y, Yuan XY, Liu WB, Li YR, Yu GX, Tian XY, Zhang YB, Fu XJ, Zhang SY. Song J, et al. Among authors: tian xy. Eur J Med Chem. 2021 Dec 5;225:113801. doi: 10.1016/j.ejmech.2021.113801. Epub 2021 Aug 26. Eur J Med Chem. 2021. PMID: 34455358

5

Design, synthesis and evaluation of novel bis-substituted aromatic amide dithiocarbamate derivatives as colchicine site tubulin polymerization inhibitors with potent anticancer activities.

Sun YX, Song J, Kong LJ, Sha BB, Tian XY, Liu XJ, Hu T, Chen P, Zhang SY. Sun YX, et al. Among authors: tian xy. Eur J Med Chem. 2022 Feb 5;229:114069. doi: 10.1016/j.ejmech.2021.114069. Epub 2021 Dec 24. Eur J Med Chem. 2022. PMID: 34971875

6

Discovery of novel coumarin-indole derivatives as tubulin polymerization inhibitors with potent anti-gastric cancer activities.

Song J, Guan YF, Liu WB, Song CH, Tian XY, Zhu T, Fu XJ, Qi YQ, Zhang SY. Song J, et al. Among authors: tian xy. Eur J Med Chem. 2022 Aug 5;238:114467. doi: 10.1016/j.ejmech.2022.114467. Epub 2022 May 18. Eur J Med Chem. 2022. PMID: 35605363

7

Discovery of N-benzylarylamide derivatives as novel tubulin polymerization inhibitors capable of activating the Hippo pathway.

Song J, Wang SH, Song CH, Zhang WX, Zhu JX, Tian XY, Fu XJ, Xu Y, Jin CY, Zhang SY. Song J, et al. Among authors: tian xy. Eur J Med Chem. 2022 Oct 5;240:114583. doi: 10.1016/j.ejmech.2022.114583. Epub 2022 Jul 7. Eur J Med Chem. 2022. PMID: 35834904

8

Design, Synthesis and Biological Evaluation of [1,2,4]Triazolo[1,5-a]pyrimidine Indole Derivatives against Gastric Cancer Cells MGC-803 via the Suppression of ERK Signaling Pathway.

Yu GX, Hu Y, Zhang WX, Tian XY, Zhang SY, Zhang Y, Yuan S, Song J. Yu GX, et al. Among authors: tian xy. Molecules. 2022 Aug 5;27(15):4996. doi: 10.3390/molecules27154996. Molecules. 2022. PMID: 35956943 Free PMC article.

9

The dual FAK-HDAC inhibitor MY-1259 displays potent activities in gastric cancers in vitro and in vivo.

Song J, Liu X, Zhang YF, Tian XY, Deng MY, Huang CZ, Zhang SY. Song J, et al. Among authors: tian xy. Bioorg Chem. 2023 Feb;131:106328. doi: 10.1016/j.bioorg.2022.106328. Epub 2022 Dec 17. Bioorg Chem. 2023. PMID: 36542986

10

Discovery of a novel Coumarin-Dihydroquinoxalone derivative MY-673 as a tubulin polymerization inhibitor capable of inhibiting the ERK pathway with potent anti-gastric cancer activities.

Song J, Wang SY, Wang X, Jia MQ, Tian XY, Fu XJ, Jin CY, Zhang SY. Song J, et al. Among authors: tian xy. Bioorg Chem. 2023 Aug;137:106580. doi: 10.1016/j.bioorg.2023.106580. Epub 2023 May 2. Bioorg Chem. 2023. PMID: 37149948

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