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Benefit of B7-1 staining and abatacept for treatment-resistant post-transplant focal segmental glomerulosclerosis in a predominantly pediatric cohort: time for a reappraisal.
Burke GW 3rd, Chandar J, Sageshima J, Ortigosa-Goggins M, Amarapurkar P, Mitrofanova A, Defreitas MJ, Katsoufis CP, Seeherunvong W, Centeno A, Pagan J, Mendez-Castaner LA, Mattiazzi AD, Kupin WL, Guerra G, Chen LJ, Morsi M, Figueiro JMG, Vianna R, Abitbol CL, Roth D, Fornoni A, Ruiz P, Ciancio G, Garin EH. Burke GW 3rd, et al. Among authors: mitrofanova a. Pediatr Nephrol. 2023 Jan;38(1):145-159. doi: 10.1007/s00467-022-05549-7. Epub 2022 May 4. Pediatr Nephrol. 2023. PMID: 35507150 Free PMC article.
Podocyte-specific GLUT4-deficient mice have fewer and larger podocytes and are protected from diabetic nephropathy.
Guzman J, Jauregui AN, Merscher-Gomez S, Maiguel D, Muresan C, Mitrofanova A, Diez-Sampedro A, Szust J, Yoo TH, Villarreal R, Pedigo C, Molano RD, Johnson K, Kahn B, Hartleben B, Huber TB, Saha J, Burke GW 3rd, Abel ED, Brosius FC, Fornoni A. Guzman J, et al. Among authors: mitrofanova a. Diabetes. 2014 Feb;63(2):701-14. doi: 10.2337/db13-0752. Epub 2013 Oct 7. Diabetes. 2014. PMID: 24101677 Free PMC article.
Sphingomyelinase-like phosphodiesterase 3b expression levels determine podocyte injury phenotypes in glomerular disease.
Yoo TH, Pedigo CE, Guzman J, Correa-Medina M, Wei C, Villarreal R, Mitrofanova A, Leclercq F, Faul C, Li J, Kretzler M, Nelson RG, Lehto M, Forsblom C, Groop PH, Reiser J, Burke GW, Fornoni A, Merscher S. Yoo TH, et al. Among authors: mitrofanova a. J Am Soc Nephrol. 2015 Jan;26(1):133-47. doi: 10.1681/ASN.2013111213. Epub 2014 Jun 12. J Am Soc Nephrol. 2015. PMID: 24925721 Free PMC article.
Nephrin Contributes to Insulin Secretion and Affects Mammalian Target of Rapamycin Signaling Independently of Insulin Receptor.
Villarreal R, Mitrofanova A, Maiguel D, Morales X, Jeon J, Grahammer F, Leibiger IB, Guzman J, Fachado A, Yoo TH, Busher Katin A, Gellermann J, Merscher S, Burke GW, Berggren PO, Oh J, Huber TB, Fornoni A. Villarreal R, et al. Among authors: mitrofanova a. J Am Soc Nephrol. 2016 Apr;27(4):1029-41. doi: 10.1681/ASN.2015020210. Epub 2015 Sep 23. J Am Soc Nephrol. 2016. PMID: 26400569 Free PMC article.
Sphingomyelinase-like phosphodiesterase 3b mediates radiation-induced damage of renal podocytes.
Ahmad A, Mitrofanova A, Bielawski J, Yang Y, Marples B, Fornoni A, Zeidan YH. Ahmad A, et al. Among authors: mitrofanova a. FASEB J. 2017 Feb;31(2):771-780. doi: 10.1096/fj.201600618R. Epub 2016 Nov 11. FASEB J. 2017. PMID: 27836988 Free PMC article.
The lipid-modulating enzyme sphingomyelin phosphodiesterase acid-like 3B (SMPDL3b) is a key determinant of podocyte injury and a known off target of the anti-CD20 antibody rituximab (RTX). ...-Ahmad, A., Mitrofanova, A., Bielawski, J., Yang, Y., …
The lipid-modulating enzyme sphingomyelin phosphodiesterase acid-like 3B (SMPDL3b) is a key determinant of podocyte injury and a
Hydroxypropyl-β-cyclodextrin protects from kidney disease in experimental Alport syndrome and focal segmental glomerulosclerosis.
Mitrofanova A, Molina J, Varona Santos J, Guzman J, Morales XA, Ducasa GM, Bryn J, Sloan A, Volosenco I, Kim JJ, Ge M, Mallela SK, Kretzler M, Eddy S, Martini S, Wahl P, Pastori S, Mendez AJ, Burke GW, Merscher S, Fornoni A. Mitrofanova A, et al. Kidney Int. 2018 Dec;94(6):1151-1159. doi: 10.1016/j.kint.2018.06.031. Epub 2018 Oct 6. Kidney Int. 2018. PMID: 30301568 Free PMC article.
ATP-binding cassette A1 deficiency causes cardiolipin-driven mitochondrial dysfunction in podocytes.
Ducasa GM, Mitrofanova A, Mallela SK, Liu X, Molina J, Sloan A, Pedigo CE, Ge M, Santos JV, Hernandez Y, Kim JJ, Maugeais C, Mendez AJ, Nair V, Kretzler M, Burke GW, Nelson RG, Ishimoto Y, Inagi R, Banerjee S, Liu S, Szeto HH, Merscher S, Fontanesi F, Fornoni A. Ducasa GM, et al. Among authors: mitrofanova a. J Clin Invest. 2019 Jul 22;129(8):3387-3400. doi: 10.1172/JCI125316. eCollection 2019 Jul 22. J Clin Invest. 2019. PMID: 31329164 Free PMC article.
Lipid mediators of insulin signaling in diabetic kidney disease.
Mitrofanova A, Sosa MA, Fornoni A. Mitrofanova A, et al. Am J Physiol Renal Physiol. 2019 Nov 1;317(5):F1241-F1252. doi: 10.1152/ajprenal.00379.2019. Epub 2019 Sep 23. Am J Physiol Renal Physiol. 2019. PMID: 31545927 Free PMC article. Review.
94 results