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CRISPR-Cas9 treatment partially restores amyloid-β 42/40 in human fibroblasts with the Alzheimer's disease PSEN 1 M146L mutation.
Konstantinidis E, Molisak A, Perrin F, Streubel-Gallasch L, Fayad S, Kim DY, Petri K, Aryee MJ, Aguilar X, György B, Giedraitis V, Joung JK, Pattanayak V, Essand M, Erlandsson A, Berezovska O, Ingelsson M. Konstantinidis E, et al. Among authors: berezovska o. Mol Ther Nucleic Acids. 2022 Mar 28;28:450-461. doi: 10.1016/j.omtn.2022.03.022. eCollection 2022 Jun 14. Mol Ther Nucleic Acids. 2022. PMID: 35505961 Free PMC article.
PS1/gamma-secretase acts as rogue chaperone of glutamate transporter EAAT2/GLT-1 in Alzheimer's disease.
Perrin F, Anderson LC, Mitchell SPC, Sinha P, Turchyna Y, Maesako M, Houser MCQ, Zhang C, Wagner SL, Tanzi RE, Berezovska O. Perrin F, et al. Among authors: berezovska o. Res Sq [Preprint]. 2023 Nov 7:rs.3.rs-3495211. doi: 10.21203/rs.3.rs-3495211/v1. Res Sq. 2023. Update in: Acta Neuropathol Commun. 2024 Oct 21;12(1):166. doi: 10.1186/s40478-024-01876-y PMID: 37986905 Free PMC article. Updated. Preprint.
Glutamate Transporter 1 as a Novel Negative Regulator of Amyloid β.
Sinha P, Turchyna Y, Mitchell SPC, Sadek M, Armagan G, Perrin F, Maesako M, Berezovska O. Sinha P, et al. Among authors: berezovska o. Cells. 2024 Sep 24;13(19):1600. doi: 10.3390/cells13191600. Cells. 2024. PMID: 39404364 Free PMC article.
95 results