Chen G - Search Results

1

Activation and allosteric regulation of the orphan GPR88-Gi1 signaling complex.

Chen G, Xu J, Inoue A, Schmidt MF, Bai C, Lu Q, Gmeiner P, Liu Z, Du Y. Chen G, et al. Nat Commun. 2022 May 2;13(1):2375. doi: 10.1038/s41467-022-30081-5. Nat Commun. 2022. PMID: 35501348 Free PMC article.

2

Cryo-EM structure of activated bile acids receptor TGR5 in complex with stimulatory G protein.

Chen G, Wang X, Ge Y, Ma L, Chen Q, Liu H, Du Y, Ye RD, Hu H, Ren R. Chen G, et al. Among authors: chen q. Signal Transduct Target Ther. 2020 Aug 3;5(1):142. doi: 10.1038/s41392-020-00262-z. Signal Transduct Target Ther. 2020. PMID: 32747649 Free PMC article. No abstract available.

3

Predicting Mutational Effects on Receptor Binding of the Spike Protein of SARS-CoV-2 Variants.

Bai C, Wang J, Chen G, Zhang H, An K, Xu P, Du Y, Ye RD, Saha A, Zhang A, Warshel A. Bai C, et al. Among authors: chen g. J Am Chem Soc. 2021 Oct 27;143(42):17646-17654. doi: 10.1021/jacs.1c07965. Epub 2021 Oct 14. J Am Chem Soc. 2021. PMID: 34648291 Free PMC article.

4

Structural insights into ligand recognition, activation, and signaling of the α_2A adrenergic receptor.

Xu J, Cao S, Hübner H, Weikert D, Chen G, Lu Q, Yuan D, Gmeiner P, Liu Z, Du Y. Xu J, et al. Among authors: chen g. Sci Adv. 2022 Mar 4;8(9):eabj5347. doi: 10.1126/sciadv.abj5347. Epub 2022 Mar 4. Sci Adv. 2022. PMID: 35245122 Free PMC article.

5

Structural basis for recognition of N-formyl peptides as pathogen-associated molecular patterns.

Chen G, Wang X, Liao Q, Ge Y, Jiao H, Chen Q, Liu Y, Lyu W, Zhu L, van Zundert GCP, Robertson MJ, Skiniotis G, Du Y, Hu H, Ye RD. Chen G, et al. Among authors: chen q. Nat Commun. 2022 Sep 5;13(1):5232. doi: 10.1038/s41467-022-32822-y. Nat Commun. 2022. PMID: 36064945 Free PMC article.

6

Cryo-EM structure of G-protein-coupled receptor GPR17 in complex with inhibitory G protein.

Ye F, Wong TS, Chen G, Zhang Z, Zhang B, Gan S, Gao W, Li J, Wu Z, Pan X, Du Y. Ye F, et al. Among authors: chen g. MedComm (2020). 2022 Sep 10;3(4):e159. doi: 10.1002/mco2.159. eCollection 2022 Dec. MedComm (2020). 2022. PMID: 36105372 Free PMC article.

7

Structure-based discovery of nonopioid analgesics acting through the α_2A-adrenergic receptor.

Fink EA, Xu J, Hübner H, Braz JM, Seemann P, Avet C, Craik V, Weikert D, Schmidt MF, Webb CM, Tolmachova NA, Moroz YS, Huang XP, Kalyanaraman C, Gahbauer S, Chen G, Liu Z, Jacobson MP, Irwin JJ, Bouvier M, Du Y, Shoichet BK, Basbaum AI, Gmeiner P. Fink EA, et al. Among authors: chen g. Science. 2022 Sep 30;377(6614):eabn7065. doi: 10.1126/science.abn7065. Epub 2022 Sep 30. Science. 2022. PMID: 36173843 Free PMC article.

8

Identification of a Sialosides binding pocket in early-lineage SARS-CoV-2 via an optimized STD NMR method: a novel explanation for coronavirus virulence and zoonosis.

Chen G, Gao W, Du Y. Chen G, et al. Mol Biomed. 2022 Oct 21;3(1):32. doi: 10.1186/s43556-022-00093-0. Mol Biomed. 2022. PMID: 36269443 Free PMC article. No abstract available.

9

Cryo-EM structure of orphan G protein-coupled receptor GPR21.

Wong TS, Gao W, Chen G, Qiu C, He G, Ye F, Wu Z, Zeng Z, Du Y. Wong TS, et al. Among authors: chen g. MedComm (2020). 2023 Jan 25;4(1):e205. doi: 10.1002/mco2.205. eCollection 2023 Feb. MedComm (2020). 2023. PMID: 36721851 Free PMC article.

10

Cryo-EM structure of the human chemerin receptor 1-Gi protein complex bound to the C-terminal nonapeptide of chemerin.

Wang J, Chen G, Liao Q, Lyu W, Liu A, Zhu L, Du Y, Ye RD. Wang J, et al. Among authors: chen g. Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2214324120. doi: 10.1073/pnas.2214324120. Epub 2023 Mar 7. Proc Natl Acad Sci U S A. 2023. PMID: 36881626 Free PMC article.

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