Li JC - Search Results

1

Selective bromodomain and extra-terminal bromodomain inhibitor inactivates macrophages and hepatic stellate cells to inhibit liver inflammation and fibrosis.

Fu R, Zu SJ, Liu YJ, Li JC, Dang WZ, Liao LP, Liu LP, Chen PY, Huang HM, Wu KH, Zhou B, Pan Q, Luo C, Zhang YY, Li GM. Fu R, et al. Among authors: li gm, li jc. Bioengineered. 2022 Apr;13(4):10914-10930. doi: 10.1080/21655979.2022.2066756. Bioengineered. 2022. PMID: 35499161 Free PMC article.

2

p300/CBP inhibitor A-485 alleviates acute liver injury by regulating macrophage activation and polarization.

Peng J, Li J, Huang J, Xu P, Huang H, Liu Y, Yu L, Yang Y, Zhou B, Jiang H, Chen K, Dang Y, Zhang Y, Luo C, Li G. Peng J, et al. Theranostics. 2019 Oct 22;9(26):8344-8361. doi: 10.7150/thno.30707. eCollection 2019. Theranostics. 2019. PMID: 31754401 Free PMC article.

3

Design, synthesis, and biological evaluation of 4-benzoylamino-1H-pyrazole-3-carboxamide derivatives as potent CDK2 inhibitors.

Lin T, Li J, Liu L, Li Y, Jiang H, Chen K, Xu P, Luo C, Zhou B. Lin T, et al. Eur J Med Chem. 2021 Apr 5;215:113281. doi: 10.1016/j.ejmech.2021.113281. Epub 2021 Feb 11. Eur J Med Chem. 2021. PMID: 33611192

4

Cyclin-dependent kinase inhibitor roscovitine attenuates liver inflammation and fibrosis by influencing initiating steps of liver injury.

Liu Y, Li J, Liao L, Huang H, Fan S, Fu R, Huang J, Shi C, Yu L, Chen KX, Zhang YY, Luo C, Li GM. Liu Y, et al. Clin Sci (Lond). 2021 Apr 16;135(7):925-941. doi: 10.1042/CS20201111. Clin Sci (Lond). 2021. PMID: 33786590

5

P300/CBP inhibition sensitizes mantle cell lymphoma to PI3Kδ inhibitor idelalisib.

Zhou XR, Li X, Liao LP, Han J, Huang J, Li JC, Tao HR, Fan SJ, Chen ZF, Li Q, Chen SJ, Ding H, Yang YX, Zhou B, Jiang HL, Chen KX, Zhang YY, Huang CX, Luo C. Zhou XR, et al. Among authors: li x, li q, li jc. Acta Pharmacol Sin. 2022 Feb;43(2):457-469. doi: 10.1038/s41401-021-00643-2. Epub 2021 Apr 13. Acta Pharmacol Sin. 2022. PMID: 33850273 Free PMC article.

6

Computational and Structure-Based Development of High Potent Cell-Active Covalent Inhibitor Targeting the Peptidyl-Prolyl Isomerase NIMA-Interacting-1 (Pin1).

Liu L, Zhu R, Li J, Pei Y, Wang S, Xu P, Wang M, Wen Y, Zhang H, Du D, Ding H, Jiang H, Chen K, Zhou B, Yu L, Luo C. Liu L, et al. J Med Chem. 2022 Feb 10;65(3):2174-2190. doi: 10.1021/acs.jmedchem.1c01686. Epub 2022 Jan 28. J Med Chem. 2022. PMID: 35089030

7

Discovery of Small-Molecule Degraders of the CDK9-Cyclin T1 Complex for Targeting Transcriptional Addiction in Prostate Cancer.

Li J, Liu T, Song Y, Wang M, Liu L, Zhu H, Li Q, Lin J, Jiang H, Chen K, Zhao K, Wang M, Zhou H, Lin H, Luo C. Li J, et al. J Med Chem. 2022 Aug 25;65(16):11034-11057. doi: 10.1021/acs.jmedchem.2c00257. Epub 2022 Aug 4. J Med Chem. 2022. PMID: 35925880

8

A potent PGK1 antagonist reveals PGK1 regulates the production of IL-1β and IL-6.

Liao L, Dang W, Lin T, Yu J, Liu T, Li W, Xiao S, Feng L, Huang J, Fu R, Li J, Liu L, Wang M, Tao H, Jiang H, Chen K, Diao X, Zhou B, Shen X, Luo C. Liao L, et al. Acta Pharm Sin B. 2022 Nov;12(11):4180-4192. doi: 10.1016/j.apsb.2022.05.012. Epub 2022 May 14. Acta Pharm Sin B. 2022. PMID: 36386479 Free PMC article.

9

Proton pump inhibitor ilaprazole suppresses cancer growth by targeting T-cell-originated protein kinase.

Zheng M, Luan S, Gao S, Cheng L, Hao B, Li J, Chen Y, Hou X, Chen L, Li H. Zheng M, et al. Oncotarget. 2017 Jun 13;8(24):39143-39153. doi: 10.18632/oncotarget.16609. Oncotarget. 2017. PMID: 28388576 Free PMC article.

10

Oral Administration of Omega-3 Fatty Acids Attenuates Lung Injury Caused by PM2.5 Respiratory Inhalation Simply and Feasibly In Vivo.

Li J, Mao M, Li J, Chen Z, Ji Y, Kong J, Wang Z, Zhang J, Wang Y, Liang W, Liang H, Lv L, Liu Q, Yan R, Yuan H, Chen K, Chang Y, Chen G, Xing G. Li J, et al. Int J Mol Sci. 2022 May 10;23(10):5323. doi: 10.3390/ijms23105323. Int J Mol Sci. 2022. PMID: 35628131 Free PMC article.

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