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Overcoming differential tumor penetration of BRAF inhibitors using computationally guided combination therapy.
Ng TSC, Hu H, Kronister S, Lee C, Li R, Gerosa L, Stopka SA, Burgenske DM, Khurana I, Regan MS, Vallabhaneni S, Putta N, Scott E, Matvey D, Giobbie-Hurder A, Kohler RH, Sarkaria JN, Parangi S, Sorger PK, Agar NYR, Jacene HA, Sullivan RJ, Buchbinder E, Mikula H, Weissleder R, Miller MA. Ng TSC, et al. Among authors: scott e. Sci Adv. 2022 Apr 29;8(17):eabl6339. doi: 10.1126/sciadv.abl6339. Epub 2022 Apr 29. Sci Adv. 2022. PMID: 35486732 Free PMC article.
Radiation Cleaved Drug-Conjugate Linkers Enable Local Payload Release.
Quintana JM, Arboleda D, Hu H, Scott E, Luthria G, Pai S, Parangi S, Weissleder R, Miller MA. Quintana JM, et al. Among authors: scott e. Bioconjug Chem. 2022 Aug 17;33(8):1474-1484. doi: 10.1021/acs.bioconjchem.2c00174. Epub 2022 Jul 14. Bioconjug Chem. 2022. PMID: 35833631 Free PMC article.
Hybrid LNP Prime Dendritic Cells for Nucleotide Delivery.
Das R, Halabi EA, Fredrich IR, Oh J, Peterson HM, Ge X, Scott E, Kohler RH, Garris CS, Weissleder R. Das R, et al. Among authors: scott e. Adv Sci (Weinh). 2023 Nov;10(33):e2303576. doi: 10.1002/advs.202303576. Epub 2023 Oct 9. Adv Sci (Weinh). 2023. PMID: 37814359 Free PMC article.
Extended Pharmacokinetics Improve Site-Specific Prodrug Activation Using Radiation.
Quintana JM, Kang M, Hu H, Ng TSC, Wojtkiewicz GR, Scott E, Parangi S, Schuemann J, Weissleder R, Miller MA. Quintana JM, et al. Among authors: scott e. ACS Cent Sci. 2024 Jun 21;10(7):1371-1382. doi: 10.1021/acscentsci.4c00354. eCollection 2024 Jul 24. ACS Cent Sci. 2024. PMID: 39071065 Free PMC article.
Scission-Enhanced Molecular Imaging (SEMI).
Quintana JM, Carlson JCT, Scott E, Ng TSC, Miller MA, Weissleder R. Quintana JM, et al. Among authors: scott e. Bioconjug Chem. 2024 Sep 10;35(10):1543-52. doi: 10.1021/acs.bioconjchem.4c00337. Online ahead of print. Bioconjug Chem. 2024. PMID: 39255972
An ultra-conserved poison exon in the Tra2b gene encoding a splicing activator is essential for male fertility and meiotic cell division.
Dalgliesh C, Aldalaqan S, Atallah C, Best A, Scott E, Ehrmann I, Merces G, Mannion J, Badurova B, Sandher R, Illing Y, Wirth B, Wells S, Codner G, Teboul L, Smith GR, Hedley A, Herbert M, de Rooij DG, Miles C, Reynard LN, Elliott DJ. Dalgliesh C, et al. Among authors: scott e. EMBO J. 2025 Jan 2. doi: 10.1038/s44318-024-00344-6. Online ahead of print. EMBO J. 2025. PMID: 39748121 Free article.
2,627 results