Saini H - Search Results

1

Leveraging omic features with F3UTER enables identification of unannotated 3'UTRs for synaptic genes.

Sethi S, Zhang D, Guelfi S, Chen Z, Garcia-Ruiz S, Olagbaju EO, Ryten M, Saini H, Botia JA. Sethi S, et al. Among authors: saini h. Nat Commun. 2022 Apr 27;13(1):2270. doi: 10.1038/s41467-022-30017-z. Nat Commun. 2022. PMID: 35477703 Free PMC article.

2

The role of SQSTM1 (p62) in mitochondrial function and clearance in human cortical neurons.

Poon A, Saini H, Sethi S, O'Sullivan GA, Plun-Favreau H, Wray S, Dawson LA, McCarthy JM. Poon A, et al. Among authors: saini h. Stem Cell Reports. 2021 May 11;16(5):1276-1289. doi: 10.1016/j.stemcr.2021.03.030. Epub 2021 Apr 22. Stem Cell Reports. 2021. PMID: 33891871 Free PMC article.

3

COSMIC-3D provides structural perspectives on cancer genetics for drug discovery.

Jubb HC, Saini HK, Verdonk ML, Forbes SA. Jubb HC, et al. Nat Genet. 2018 Sep;50(9):1200-1202. doi: 10.1038/s41588-018-0214-9. Nat Genet. 2018. PMID: 30158682 Free PMC article.

4

Detection of secondary binding sites in proteins using fragment screening.

Ludlow RF, Verdonk ML, Saini HK, Tickle IJ, Jhoti H. Ludlow RF, et al. Among authors: saini hk. Proc Natl Acad Sci U S A. 2015 Dec 29;112(52):15910-5. doi: 10.1073/pnas.1518946112. Epub 2015 Dec 11. Proc Natl Acad Sci U S A. 2015. PMID: 26655740 Free PMC article.

5

Integrated analysis of microRNA and mRNA expression and association with HIF binding reveals the complexity of microRNA expression regulation under hypoxia.

Camps C, Saini HK, Mole DR, Choudhry H, Reczko M, Guerra-Assunção JA, Tian YM, Buffa FM, Harris AL, Hatzigeorgiou AG, Enright AJ, Ragoussis J. Camps C, et al. Among authors: saini hk. Mol Cancer. 2014 Feb 11;13:28. doi: 10.1186/1476-4598-13-28. Mol Cancer. 2014. PMID: 24517586 Free PMC article.

6

Visualization and analysis of RNA-Seq assembly graphs.

Nazarie FW, Shih B, Angus T, Barnett MW, Chen SH, Summers KM, Klein K, Faulkner GJ, Saini HK, Watson M, Dongen SV, Enright AJ, Freeman TC. Nazarie FW, et al. Nucleic Acids Res. 2019 Aug 22;47(14):7262-7275. doi: 10.1093/nar/gkz599. Nucleic Acids Res. 2019. PMID: 31305886 Free PMC article.

7

Fragment-Based Discovery of a Potent, Orally Bioavailable Inhibitor That Modulates the Phosphorylation and Catalytic Activity of ERK1/2.

Heightman TD, Berdini V, Braithwaite H, Buck IM, Cassidy M, Castro J, Courtin A, Day JEH, East C, Fazal L, Graham B, Griffiths-Jones CM, Lyons JF, Martins V, Muench S, Munck JM, Norton D, O'Reilly M, Palmer N, Pathuri P, Reader M, Rees DC, Rich SJ, Richardson C, Saini H, Thompson NT, Wallis NG, Walton H, Wilsher NE, Woolford AJ, Cooke M, Cousin D, Onions S, Shannon J, Watts J, Murray CW. Heightman TD, et al. Among authors: saini h. J Med Chem. 2018 Jun 14;61(11):4978-4992. doi: 10.1021/acs.jmedchem.8b00421. Epub 2018 May 31. J Med Chem. 2018. PMID: 29775310

8

Messenger RNA and microRNA profiling during early mouse EB formation.

Tripathi R, Saini HK, Rad R, Abreu-Goodger C, van Dongen S, Enright AJ. Tripathi R, et al. Gene Expr Patterns. 2011 Jun-Jul;11(5-6):334-44. doi: 10.1016/j.gep.2011.03.004. Epub 2011 Apr 1. Gene Expr Patterns. 2011. PMID: 21440681

9

Emergence of resistance to tyrosine kinase inhibitors in non-small-cell lung cancer can be delayed by an upfront combination with the HSP90 inhibitor onalespib.

Courtin A, Smyth T, Hearn K, Saini HK, Thompson NT, Lyons JF, Wallis NG. Courtin A, et al. Br J Cancer. 2016 Oct 25;115(9):1069-1077. doi: 10.1038/bjc.2016.294. Epub 2016 Sep 27. Br J Cancer. 2016. PMID: 27673365 Free PMC article.

10

Antagonism of inhibitors of apoptosis proteins reveals a novel, immune response-based therapeutic approach for T-cell lymphoma.

Ferrari N, Ward G, Gewinner C, Davis MP, Jueliger S, Saini H, Munck J, Smyth T, Ferraldeschi R, Keer H, Lyons J, Sims MJ. Ferrari N, et al. Among authors: saini h. Blood Adv. 2021 Oct 26;5(20):4003-4016. doi: 10.1182/bloodadvances.2020003955. Blood Adv. 2021. PMID: 34474469 Free PMC article.

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