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Gasdermin D Exerts Anti-inflammatory Effects by Promoting Neutrophil Death.
Kambara H, Liu F, Zhang X, Liu P, Bajrami B, Teng Y, Zhao L, Zhou S, Yu H, Zhou W, Silberstein LE, Cheng T, Han M, Xu Y, Luo HR. Kambara H, et al. Among authors: zhao l. Cell Rep. 2018 Mar 13;22(11):2924-2936. doi: 10.1016/j.celrep.2018.02.067. Cell Rep. 2018. PMID: 29539421 Free PMC article.
Positive Regulation of Interleukin-1β Bioactivity by Physiological ROS-Mediated Cysteine S-Glutathionylation.
Zhang X, Liu P, Zhang C, Chiewchengchol D, Zhao F, Yu H, Li J, Kambara H, Luo KY, Venkataraman A, Zhou Z, Zhou W, Zhu H, Zhao L, Sakai J, Chen Y, Ho YS, Bajrami B, Xu B, Silberstein LE, Cheng T, Xu Y, Ke Y, Luo HR. Zhang X, et al. Among authors: zhao f, zhao l. Cell Rep. 2017 Jul 5;20(1):224-235. doi: 10.1016/j.celrep.2017.05.070. Cell Rep. 2017. PMID: 28683316 Free PMC article.
Targeting multiple cell death pathways extends the shelf life and preserves the function of human and mouse neutrophils for transfusion.
Fan Y, Teng Y, Loison F, Pang A, Kasorn A, Shao X, Zhang C, Ren Q, Yu H, Zheng Y, Cancelas JA, Manis J, Chai L, Park SY, Zhao L, Xu Y, Feng S, Silberstein LE, Ma F, Luo HR. Fan Y, et al. Among authors: zhao l. Sci Transl Med. 2021 Jul 28;13(604):eabb1069. doi: 10.1126/scitranslmed.abb1069. Sci Transl Med. 2021. PMID: 34321317 Free PMC article.
FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation.
Hu JJ, Liu X, Xia S, Zhang Z, Zhang Y, Zhao J, Ruan J, Luo X, Lou X, Bai Y, Wang J, Hollingsworth LR, Magupalli VG, Zhao L, Luo HR, Kim J, Lieberman J, Wu H. Hu JJ, et al. Among authors: zhao j, zhao l. Nat Immunol. 2020 Jul;21(7):736-745. doi: 10.1038/s41590-020-0669-6. Epub 2020 May 4. Nat Immunol. 2020. PMID: 32367036 Free PMC article.
38,081 results
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