Scally S - Search Results

1

Basis for drug selectivity of plasmepsin IX and X inhibition in Plasmodium falciparum and vivax.

Hodder AN, Christensen J, Scally S, Triglia T, Ngo A, Birkinshaw RW, Bailey B, Favuzza P, Dietrich MH, Tham WH, Czabotar PE, Lowes K, Guo Z, Murgolo N, Lera Ruiz M, McCauley JA, Sleebs BE, Olsen D, Cowman AF. Hodder AN, et al. Among authors: scally s. Structure. 2022 Jul 7;30(7):947-961.e6. doi: 10.1016/j.str.2022.03.018. Epub 2022 Apr 22. Structure. 2022. PMID: 35460613 Free article.

2

PCRCR complex is essential for invasion of human erythrocytes by Plasmodium falciparum.

Scally SW, Triglia T, Evelyn C, Seager BA, Pasternak M, Lim PS, Healer J, Geoghegan ND, Adair A, Tham WH, Dagley LF, Rogers KL, Cowman AF. Scally SW, et al. Nat Microbiol. 2022 Dec;7(12):2039-2053. doi: 10.1038/s41564-022-01261-2. Epub 2022 Nov 17. Nat Microbiol. 2022. PMID: 36396942 Free PMC article.

3

Plasmepsin X activates the PCRCR complex of Plasmodium falciparum by processing PfRh5 for erythrocyte invasion.

Triglia T, Scally SW, Seager BA, Pasternak M, Dagley LF, Cowman AF. Triglia T, et al. Among authors: scally sw. Nat Commun. 2023 Apr 19;14(1):2219. doi: 10.1038/s41467-023-37890-2. Nat Commun. 2023. PMID: 37072430 Free PMC article.

4

Expression, purification, crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase from Bacillus anthracis in the presence of pyruvate.

Voss JE, Scally SW, Taylor NL, Dogovski C, Alderton MR, Hutton CA, Gerrard JA, Parker MW, Dobson RC, Perugini MA. Voss JE, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Feb 1;65(Pt 2):188-91. doi: 10.1107/S1744309109000670. Epub 2009 Jan 31. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009. PMID: 19194017 Free PMC article.

5

Substrate-mediated stabilization of a tetrameric drug target reveals Achilles heel in anthrax.

Voss JE, Scally SW, Taylor NL, Atkinson SC, Griffin MD, Hutton CA, Parker MW, Alderton MR, Gerrard JA, Dobson RC, Dogovski C, Perugini MA. Voss JE, et al. J Biol Chem. 2010 Feb 19;285(8):5188-95. doi: 10.1074/jbc.M109.038166. Epub 2009 Nov 30. J Biol Chem. 2010. PMID: 19948665 Free PMC article.

6

Characterisation of dihydrodipicolinate synthase (DHDPS) from Bacillus anthracis.

Domigan LJ, Scally SW, Fogg MJ, Hutton CA, Perugini MA, Dobson RC, Muscroft-Taylor AC, Gerrard JA, Devenish SR. Domigan LJ, et al. Among authors: scally sw. Biochim Biophys Acta. 2009 Oct;1794(10):1510-6. doi: 10.1016/j.bbapap.2009.06.020. Epub 2009 Jul 10. Biochim Biophys Acta. 2009. PMID: 19595801

7

Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs.

Murugan R, Scally SW, Costa G, Mustafa G, Thai E, Decker T, Bosch A, Prieto K, Levashina EA, Julien JP, Wardemann H. Murugan R, et al. Among authors: scally sw. Nat Med. 2020 Jul;26(7):1135-1145. doi: 10.1038/s41591-020-0881-9. Epub 2020 May 25. Nat Med. 2020. PMID: 32451496

8

A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity.

Thai E, Costa G, Weyrich A, Murugan R, Oyen D, Flores-Garcia Y, Prieto K, Bosch A, Valleriani A, Wu NC, Pholcharee T, Scally SW, Wilson IA, Wardemann H, Julien JP, Levashina EA. Thai E, et al. Among authors: scally sw. J Exp Med. 2020 Nov 2;217(11):e20200061. doi: 10.1084/jem.20200061. J Exp Med. 2020. PMID: 32790871 Free PMC article.

9

Key Residues at Third CDR3β Position Impact Structure and Antigen Recognition of Human Invariant NK TCRs.

Chamoto K, Guo T, Scally SW, Kagoya Y, Anczurowski M, Wang CH, Rahman MA, Saso K, Butler MO, Chiu PP, Julien JP, Hirano N. Chamoto K, et al. J Immunol. 2017 Feb 1;198(3):1056-1065. doi: 10.4049/jimmunol.1601556. Epub 2016 Dec 21. J Immunol. 2017. PMID: 28003379 Free PMC article.

10

Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.

Scally SW, McLeod B, Bosch A, Miura K, Liang Q, Carroll S, Reponen S, Nguyen N, Giladi E, Rämisch S, Yusibov V, Bradley A, Lemiale F, Schief WR, Emerling D, Kellam P, King CR, Julien JP. Scally SW, et al. Nat Commun. 2017 Nov 16;8(1):1568. doi: 10.1038/s41467-017-01924-3. Nat Commun. 2017. PMID: 29146922 Free PMC article.

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