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Neutron-upscattering enhancement of the triple-alpha process.
Bishop J, Parker CE, Rogachev GV, Ahn S, Koshchiy E, Brandenburg K, Brune CR, Charity RJ, Derkin J, Dronchi N, Hamad G, Jones-Alberty Y, Kokalova T, Massey TN, Meisel Z, Ohstrom EV, Paneru SN, Pollacco EC, Saxena M, Singh N, Smith R, Sobotka LG, Soltesz D, Subedi SK, Voinov AV, Warren J, Wheldon C. Bishop J, et al. Among authors: saxena m. Nat Commun. 2022 Apr 20;13(1):2151. doi: 10.1038/s41467-022-29848-7. Nat Commun. 2022. PMID: 35444209 Free PMC article.
A presenilin dimer at the core of the gamma-secretase enzyme: insights from parallel analysis of Notch 1 and APP proteolysis.
Schroeter EH, Ilagan MX, Brunkan AL, Hecimovic S, Li YM, Xu M, Lewis HD, Saxena MT, De Strooper B, Coonrod A, Tomita T, Iwatsubo T, Moore CL, Goate A, Wolfe MS, Shearman M, Kopan R. Schroeter EH, et al. Among authors: saxena mt. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):13075-80. doi: 10.1073/pnas.1735338100. Epub 2003 Oct 17. Proc Natl Acad Sci U S A. 2003. PMID: 14566063 Free PMC article.
NTR 2.0: a rationally engineered prodrug-converting enzyme with substantially enhanced efficacy for targeted cell ablation.
Sharrock AV, Mulligan TS, Hall KR, Williams EM, White DT, Zhang L, Emmerich K, Matthews F, Nimmagadda S, Washington S, Le KD, Meir-Levi D, Cox OL, Saxena MT, Calof AL, Lopez-Burks ME, Lander AD, Ding D, Ji H, Ackerley DF, Mumm JS. Sharrock AV, et al. Among authors: saxena mt. Nat Methods. 2022 Feb;19(2):205-215. doi: 10.1038/s41592-021-01364-4. Epub 2022 Feb 7. Nat Methods. 2022. PMID: 35132245 Free PMC article.
Large-scale phenotypic drug screen identifies neuroprotectants in zebrafish and mouse models of retinitis pigmentosa.
Zhang L, Chen C, Fu J, Lilley B, Berlinicke C, Hansen B, Ding D, Wang G, Wang T, Shou D, Ye Y, Mulligan T, Emmerich K, Saxena MT, Hall KR, Sharrock AV, Brandon C, Park H, Kam TI, Dawson VL, Dawson TM, Shim JS, Hanes J, Ji H, Liu JO, Qian J, Ackerley DF, Rohrer B, Zack DJ, Mumm JS. Zhang L, et al. Among authors: saxena mt. Elife. 2021 Jun 29;10:e57245. doi: 10.7554/eLife.57245. Elife. 2021. PMID: 34184634 Free PMC article.
727 results