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Page 1
Broadly neutralizing antibodies target the coronavirus fusion peptide.
Dacon C, Tucker C, Peng L, Lee CD, Lin TH, Yuan M, Cong Y, Wang L, Purser L, Williams JK, Pyo CW, Kosik I, Hu Z, Zhao M, Mohan D, Cooper A, Peterson M, Skinner J, Dixit S, Kollins E, Huzella L, Perry D, Byrum R, Lembirik S, Zhang Y, Yang ES, Chen M, Leung K, Weinberg RS, Pegu A, Geraghty DE, Davidson E, Douagi I, Moir S, Yewdell JW, Schmaljohn C, Crompton PD, Holbrook MR, Nemazee D, Mascola JR, Wilson IA, Tan J. Dacon C, et al. Among authors: nemazee d. bioRxiv [Preprint]. 2022 Apr 12:2022.04.11.487879. doi: 10.1101/2022.04.11.487879. bioRxiv. 2022. Update in: Science. 2022 Aug 12;377(6607):728-735. doi: 10.1126/science.abq3773 PMID: 35441178 Free PMC article. Updated. Preprint.
Ultrapotent bispecific antibodies neutralize emerging SARS-CoV-2 variants.
Cho H, Gonzales-Wartz KK, Huang D, Yuan M, Peterson M, Liang J, Beutler N, Torres JL, Cong Y, Postnikova E, Bangaru S, Talana CA, Shi W, Yang ES, Zhang Y, Leung K, Wang L, Peng L, Skinner J, Li S, Wu NC, Liu H, Dacon C, Moyer T, Cohen M, Zhao M, Lee FE, Weinberg RS, Douagi I, Gross R, Schmaljohn C, Pegu A, Mascola JR, Holbrook M, Nemazee D, Rogers TF, Ward AB, Wilson IA, Crompton PD, Tan J. Cho H, et al. Among authors: nemazee d. bioRxiv [Preprint]. 2021 Apr 1:2021.04.01.437942. doi: 10.1101/2021.04.01.437942. bioRxiv. 2021. Update in: Sci Transl Med. 2021 Oct 20;13(616):eabj5413. doi: 10.1126/scitranslmed.abj5413 PMID: 33821267 Free PMC article. Updated. Preprint.
A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection.
Zhou P, Yuan M, Song G, Beutler N, Shaabani N, Huang D, He WT, Zhu X, Callaghan S, Yong P, Anzanello F, Peng L, Ricketts J, Parren M, Garcia E, Rawlings SA, Smith DM, Nemazee D, Teijaro JR, Rogers TF, Wilson IA, Burton DR, Andrabi R. Zhou P, et al. Among authors: nemazee d. bioRxiv [Preprint]. 2022 Jan 21:2021.03.30.437769. doi: 10.1101/2021.03.30.437769. bioRxiv. 2022. Update in: Sci Transl Med. 2022 Mar 23;14(637):eabi9215. doi: 10.1126/scitranslmed.abi9215 PMID: 33821273 Free PMC article. Updated. Preprint.
Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause severe disease.
Zhou P, Song G, He WT, Beutler N, Tse LV, Martinez DR, Schäfer A, Anzanello F, Yong P, Peng L, Dueker K, Musharrafieh R, Callaghan S, Capozzola T, Yuan M, Liu H, Limbo O, Parren M, Garcia E, Rawlings SA, Smith DM, Nemazee D, Jardine JG, Wilson IA, Safonova Y, Rogers TF, Baric RS, Gralinski LE, Burton DR, Andrabi R. Zhou P, et al. Among authors: nemazee d. bioRxiv [Preprint]. 2022 Mar 7:2022.03.04.479488. doi: 10.1101/2022.03.04.479488. bioRxiv. 2022. Update in: Immunity. 2023 Mar 14;56(3):669-686.e7. doi: 10.1016/j.immuni.2023.02.005 PMID: 35291291 Free PMC article. Updated. Preprint.
A broad and potent neutralization epitope in SARS-related coronaviruses.
Yuan M, Zhu X, He WT, Zhou P, Kaku CI, Capozzola T, Zhu CY, Yu X, Liu H, Yu W, Hua Y, Tien H, Peng L, Song G, Cottrell CA, Schief WR, Nemazee D, Walker LM, Andrabi R, Burton DR, Wilson IA. Yuan M, et al. Among authors: nemazee d. bioRxiv [Preprint]. 2022 Mar 14:2022.03.13.484037. doi: 10.1101/2022.03.13.484037. bioRxiv. 2022. Update in: Proc Natl Acad Sci U S A. 2022 Jul 19;119(29):e2205784119. doi: 10.1073/pnas.2205784119 PMID: 35313576 Free PMC article. Updated. Preprint.
Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift.
Song G, Yuan M, Liu H, Capozzola T, Lin RN, Torres JL, He WT, Musharrafieh R, Dueker K, Zhou P, Callaghan S, Mishra N, Yong P, Anzanello F, Avillion G, Vo AL, Li X, Makhdoomi M, Feng Z, Zhu X, Peng L, Nemazee D, Safonova Y, Briney B, Ward AB, Burton DR, Wilson IA, Andrabi R. Song G, et al. Among authors: nemazee d. bioRxiv [Preprint]. 2023 Apr 27:2023.04.26.538488. doi: 10.1101/2023.04.26.538488. bioRxiv. 2023. PMID: 37162858 Free PMC article. Preprint.
SARS-CoV-2 Serology Status Detected by Commercialized Platforms Distinguishes Previous Infection and Vaccination Adaptive Immune Responses.
Suhandynata RT, Bevins NJ, Tran JT, Huang D, Hoffman MA, Lund K, Kelner MJ, McLawhon RW, Gonias SL, Nemazee D, Fitzgerald RL. Suhandynata RT, et al. Among authors: nemazee d. medRxiv [Preprint]. 2021 Mar 12:2021.03.10.21253299. doi: 10.1101/2021.03.10.21253299. medRxiv. 2021. Update in: J Appl Lab Med. 2021 Sep 1;6(5):1109-1122. doi: 10.1093/jalm/jfab080 PMID: 33758902 Free PMC article. Updated. Preprint.
Interleukin-2-secreting T helper cells promote extra-follicular B cell maturation via intrinsic regulation of a B cell mTOR-AKT-Blimp-1 axis.
Faliti CE, Mesina M, Choi J, Bélanger S, Marshall MA, Tipton CM, Hicks S, Chappa P, Cardenas MA, Abdel-Hakeem M, Thinnes TC, Cottrell C, Scharer CD, Schief WR, Nemazee D, Woodruff MC, Lindner JM, Sanz I, Crotty S. Faliti CE, et al. Among authors: nemazee d. Immunity. 2024 Dec 10;57(12):2772-2789.e8. doi: 10.1016/j.immuni.2024.11.006. Epub 2024 Nov 28. Immunity. 2024. PMID: 39612915
Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4.
Yuan M, Peng L, Huang D, Gavin A, Luan F, Tran J, Feng Z, Zhu X, Matteson J, Wilson IA, Nemazee D. Yuan M, et al. Among authors: nemazee d. bioRxiv [Preprint]. 2023 Nov 20:2023.11.20.567917. doi: 10.1101/2023.11.20.567917. bioRxiv. 2023. Update in: Structure. 2024 Jun 6;32(6):766-779.e7. doi: 10.1016/j.str.2024.02.019 PMID: 38045427 Free PMC article. Updated. Preprint.
176 results