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Page 1
Broadly neutralizing antibodies target the coronavirus fusion peptide.
Dacon C, Tucker C, Peng L, Lee CD, Lin TH, Yuan M, Cong Y, Wang L, Purser L, Williams JK, Pyo CW, Kosik I, Hu Z, Zhao M, Mohan D, Cooper A, Peterson M, Skinner J, Dixit S, Kollins E, Huzella L, Perry D, Byrum R, Lembirik S, Zhang Y, Yang ES, Chen M, Leung K, Weinberg RS, Pegu A, Geraghty DE, Davidson E, Douagi I, Moir S, Yewdell JW, Schmaljohn C, Crompton PD, Holbrook MR, Nemazee D, Mascola JR, Wilson IA, Tan J. Dacon C, et al. Among authors: geraghty de. bioRxiv [Preprint]. 2022 Apr 12:2022.04.11.487879. doi: 10.1101/2022.04.11.487879. bioRxiv. 2022. Update in: Science. 2022 Aug 12;377(6607):728-735. doi: 10.1126/science.abq3773 PMID: 35441178 Free PMC article. Updated. Preprint.
Tracking SARS-CoV-2 Spike Protein Mutations in the United States (2020/01 - 2021/03) Using a Statistical Learning Strategy.
Zhao LP, Lybrand TP, Gilbert PB, Hawn TR, Schiffer JT, Stamatatos L, Payne TH, Carpp LN, Geraghty DE, Jerome KR. Zhao LP, et al. Among authors: geraghty de. bioRxiv [Preprint]. 2021 Jun 15:2021.06.15.448495. doi: 10.1101/2021.06.15.448495. bioRxiv. 2021. Update in: Viruses. 2021 Dec 21;14(1):9. doi: 10.3390/v14010009 PMID: 34159336 Free PMC article. Updated. Preprint.
Progression to type 1 diabetes in the DPT-1 and TN07 clinical trials is critically associated with specific residues in HLA-DQA1-B1 heterodimers.
Zhao LP, Papadopoulos GK, Skyler JS, Pugliese A, Parikh HM, Kwok WW, Lybrand TP, Bondinas GP, Moustakas AK, Wang R, Pyo CW, Nelson WC, Geraghty DE, Lernmark Å. Zhao LP, et al. Among authors: geraghty de. Diabetologia. 2024 Nov;67(11):2481-2493. doi: 10.1007/s00125-024-06274-6. Epub 2024 Oct 1. Diabetologia. 2024. PMID: 39354095 Free PMC article.
T cell response to intact SARS-CoV-2 includes coronavirus cross-reactive and variant-specific components.
Jing L, Wu X, Krist MP, Hsiang TY, Campbell VL, McClurkan CL, Favors SM, Hemingway LA, Godornes C, Tong DQ, Selke S, LeClair AC, Pyo CW, Geraghty DE, Laing KJ, Wald A, Gale M, Koelle DM. Jing L, et al. Among authors: geraghty de. medRxiv [Preprint]. 2022 Jan 25:2022.01.23.22269497. doi: 10.1101/2022.01.23.22269497. medRxiv. 2022. Update in: JCI Insight. 2022 Mar 22;7(6):e158126. doi: 10.1172/jci.insight.158126 PMID: 35118477 Free PMC article. Updated. Preprint.
Natural malaria infection elicits rare but potent neutralizing antibodies to the blood-stage antigen RH5.
Wang LT, Cooper AJR, Farrell B, Miura K, Diouf A, Müller-Sienerth N, Crosnier C, Purser L, Kirtley PJ, Maciuszek M, Barrett JR, McHugh K, Ogwang R, Tucker C, Li S, Doumbo S, Doumtabe D, Pyo CW, Skinner J, Nielsen CM, Silk SE, Kayentao K, Ongoiba A, Zhao M, Nguyen DC, Lee FE, Minassian AM, Geraghty DE, Traore B, Seder RA, Wilder BK, Crompton PD, Wright GJ, Long CA, Draper SJ, Higgins MK, Tan J. Wang LT, et al. Among authors: geraghty de. Cell. 2024 Sep 5;187(18):4981-4995.e14. doi: 10.1016/j.cell.2024.06.037. Epub 2024 Jul 25. Cell. 2024. PMID: 39059381 Free PMC article.
HLA Class II (DR, DQ, DP) Genes Were Separately Associated With the Progression From Seroconversion to Onset of Type 1 Diabetes Among Participants in Two Diabetes Prevention Trials (DPT-1 and TN07).
Zhao LP, Papadopoulos GK, Skyler JS, Pugliese A, Parikh HM, Kwok WW, Lybrand TP, Bondinas GP, Moustakas AK, Wang R, Pyo CW, Nelson WC, Geraghty DE, Lernmark Å. Zhao LP, et al. Among authors: geraghty de. Diabetes Care. 2024 May 1;47(5):826-834. doi: 10.2337/dc23-1947. Diabetes Care. 2024. PMID: 38498185
Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses.
Dacon C, Peng L, Lin TH, Tucker C, Lee CD, Cong Y, Wang L, Purser L, Cooper AJR, Williams JK, Pyo CW, Yuan M, Kosik I, Hu Z, Zhao M, Mohan D, Peterson M, Skinner J, Dixit S, Kollins E, Huzella L, Perry D, Byrum R, Lembirik S, Murphy M, Zhang Y, Yang ES, Chen M, Leung K, Weinberg RS, Pegu A, Geraghty DE, Davidson E, Doranz BJ, Douagi I, Moir S, Yewdell JW, Schmaljohn C, Crompton PD, Mascola JR, Holbrook MR, Nemazee D, Wilson IA, Tan J. Dacon C, et al. Among authors: geraghty de. Cell Host Microbe. 2023 Jun 14;31(6):1071-1072. doi: 10.1016/j.chom.2023.05.016. Cell Host Microbe. 2023. PMID: 37321165 Free PMC article. No abstract available.
165 results