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Discovery of the Showdomycin Gene Cluster from Streptomyces showdoensis ATCC 15227 Yields Insight into the Biosynthetic Logic of C-Nucleoside Antibiotics.
Palmu K, Rosenqvist P, Thapa K, Ilina Y, Siitonen V, Baral B, Mäkinen J, Belogurov G, Virta P, Niemi J, Metsä-Ketelä M. Palmu K, et al. Among authors: virta p. ACS Chem Biol. 2017 Jun 16;12(6):1472-1477. doi: 10.1021/acschembio.7b00078. Epub 2017 Apr 27. ACS Chem Biol. 2017. PMID: 28418235 Free article.
DNA-Templated N(Me)-Alkoxyamine Glycosylation.
Österlund T, Korhonen H, Virta P. Österlund T, et al. Among authors: virta p. Org Lett. 2018 Mar 16;20(6):1496-1499. doi: 10.1021/acs.orglett.8b00113. Epub 2018 Mar 7. Org Lett. 2018. PMID: 29513541 Free PMC article.
Oxazinomycin arrests RNA polymerase at the polythymidine sequences.
Prajapati RK, Rosenqvist P, Palmu K, Mäkinen JJ, Malinen AM, Virta P, Metsä-Ketelä M, Belogurov GA. Prajapati RK, et al. Among authors: virta p. Nucleic Acids Res. 2019 Nov 4;47(19):10296-10312. doi: 10.1093/nar/gkz782. Nucleic Acids Res. 2019. PMID: 31495891 Free PMC article.
PDE6D Inhibitors with a New Design Principle Selectively Block K-Ras Activity.
Siddiqui FA, Alam C, Rosenqvist P, Ora M, Sabt A, Manoharan GB, Bindu L, Okutachi S, Catillon M, Taylor T, Abdelhafez OM, Lönnberg H, Stephen AG, Papageorgiou AC, Virta P, Abankwa D. Siddiqui FA, et al. Among authors: virta p. ACS Omega. 2019 Dec 23;5(1):832-842. doi: 10.1021/acsomega.9b03639. eCollection 2020 Jan 14. ACS Omega. 2019. PMID: 31956834 Free PMC article.
85 results