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Brain-resident memory T cells generated early in life predispose to autoimmune disease in mice.
Steinbach K, Vincenti I, Egervari K, Kreutzfeldt M, van der Meer F, Page N, Klimek B, Rossitto-Borlat I, Di Liberto G, Muschaweckh A, Wagner I, Hammad K, Stadelmann C, Korn T, Hartley O, Pinschewer DD, Merkler D. Steinbach K, et al. Among authors: merkler d. Sci Transl Med. 2019 Jun 26;11(498):eaav5519. doi: 10.1126/scitranslmed.aav5519. Sci Transl Med. 2019. PMID: 31243152
Salivary gland macrophages and tissue-resident CD8+ T cells cooperate for homeostatic organ surveillance.
Stolp B, Thelen F, Ficht X, Altenburger LM, Ruef N, Inavalli VVGK, Germann P, Page N, Moalli F, Raimondi A, Keyser KA, Seyed Jafari SM, Barone F, Dettmer MS, Merkler D, Iannacone M, Sharpe J, Schlapbach C, Fackler OT, Nägerl UV, Stein JV. Stolp B, et al. Among authors: merkler d. Sci Immunol. 2020 Apr 3;5(46):eaaz4371. doi: 10.1126/sciimmunol.aaz4371. Sci Immunol. 2020. PMID: 32245888
Single-cell immune repertoire and transcriptome sequencing reveals that clonally expanded and transcriptionally distinct lymphocytes populate the aged central nervous system in mice.
Yermanos A, Neumeier D, Sandu I, Borsa M, Waindok AC, Merkler D, Oxenius A, Reddy ST. Yermanos A, et al. Among authors: merkler d. Proc Biol Sci. 2021 Feb 24;288(1945):20202793. doi: 10.1098/rspb.2020.2793. Epub 2021 Feb 24. Proc Biol Sci. 2021. PMID: 33622131 Free PMC article.
Profiling the specificity of clonally expanded plasma cells during chronic viral infection by single-cell analysis.
Neumeier D, Pedrioli A, Genovese A, Sandu I, Ehling R, Hong KL, Papadopoulou C, Agrafiotis A, Kuhn R, Shlesinger D, Robbiani D, Han J, Hauri L, Csepregi L, Greiff V, Merkler D, Reddy ST, Oxenius A, Yermanos A. Neumeier D, et al. Among authors: merkler d. Eur J Immunol. 2022 Feb;52(2):297-311. doi: 10.1002/eji.202149331. Epub 2021 Nov 23. Eur J Immunol. 2022. PMID: 34727578 Free PMC article.
261 results