Strenuous exercise triggers a life-threatening response in mice susceptible to malignant hyperthermia.
Michelucci A, Paolini C, Boncompagni S, Canato M, Reggiani C, Protasi F.
Michelucci A, et al.
FASEB J. 2017 Aug;31(8):3649-3662. doi: 10.1096/fj.201601292R. Epub 2017 May 2.
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PMID: 28465322
Free PMC article.
Correlation between MH susceptibility and HS is supported by extensive work in mouse models that carry a mutation in ryanodine receptor type-1 (RYR1(Y522S/WT)) and calsequestrin-1 knockout (CASQ1-null), 2 proteins that control Ca(2+) release in skeletal muscle. ...These re …
Correlation between MH susceptibility and HS is supported by extensive work in mouse models that carry a mutation in ryanodine recept …