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Page 1
HDAC Inhibition Reverses Preexisting Diastolic Dysfunction and Blocks Covert Extracellular Matrix Remodeling.
Travers JG, Wennersten SA, Peña B, Bagchi RA, Smith HE, Hirsch RA, Vanderlinden LA, Lin YH, Dobrinskikh E, Demos-Davies KM, Cavasin MA, Mestroni L, Steinkühler C, Lin CY, Houser SR, Woulfe KC, Lam MPY, McKinsey TA. Travers JG, et al. Among authors: cavasin ma. Circulation. 2021 May 11;143(19):1874-1890. doi: 10.1161/CIRCULATIONAHA.120.046462. Epub 2021 Mar 8. Circulation. 2021. PMID: 33682427 Free PMC article.
Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension.
Lemon DD, Horn TR, Cavasin MA, Jeong MY, Haubold KW, Long CS, Irwin DC, McCune SA, Chung E, Leinwand LA, McKinsey TA. Lemon DD, et al. J Mol Cell Cardiol. 2011 Jul;51(1):41-50. doi: 10.1016/j.yjmcc.2011.04.005. Epub 2011 Apr 23. J Mol Cell Cardiol. 2011. PMID: 21539845 Free PMC article.
HDAC6 modulates myofibril stiffness and diastolic function of the heart.
Lin YH, Major JL, Liebner T, Hourani Z, Travers JG, Wennersten SA, Haefner KR, Cavasin MA, Wilson CE, Jeong MY, Han Y, Gotthardt M, Ferguson SK, Ambardekar AV, Lam MP, Choudhary C, Granzier HL, Woulfe KC, McKinsey TA. Lin YH, et al. Among authors: cavasin ma. J Clin Invest. 2022 May 16;132(10):e148333. doi: 10.1172/JCI148333. J Clin Invest. 2022. PMID: 35575093 Free PMC article.
Histone deacetylase activity governs diastolic dysfunction through a nongenomic mechanism.
Jeong MY, Lin YH, Wennersten SA, Demos-Davies KM, Cavasin MA, Mahaffey JH, Monzani V, Saripalli C, Mascagni P, Reece TB, Ambardekar AV, Granzier HL, Dinarello CA, McKinsey TA. Jeong MY, et al. Among authors: cavasin ma. Sci Transl Med. 2018 Feb 7;10(427):eaao0144. doi: 10.1126/scitranslmed.aao0144. Sci Transl Med. 2018. PMID: 29437146 Free PMC article.
Acute Kidney Injury Results in Long-Term Diastolic Dysfunction That Is Prevented by Histone Deacetylase Inhibition.
Soranno DE, Kirkbride-Romeo L, Wennersten SA, Ding K, Cavasin MA, Baker P, Altmann C, Bagchi RA, Haefner KR, Steinkühler C, Montford JR, Keith B, Gist KM, McKinsey TA, Faubel S. Soranno DE, et al. Among authors: cavasin ma. JACC Basic Transl Sci. 2021 Feb 22;6(2):119-133. doi: 10.1016/j.jacbts.2020.11.013. eCollection 2021 Feb. JACC Basic Transl Sci. 2021. PMID: 33665513 Free PMC article.
47 results