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Current gene panels account for nearly all homologous recombination repair-associated multiple-case breast cancer families.
Matis TS, Zayed N, Labraki B, de Ladurantaye M, Matis TA, Camacho Valenzuela J, Hamel N, Atayan A, Rivera B, Tabach Y, Tonin PN, Orthwein A, Mes-Masson AM, El Haffaf Z, Foulkes WD, Polak P. Matis TS, et al. Among authors: polak p. NPJ Breast Cancer. 2021 Aug 25;7(1):109. doi: 10.1038/s41523-021-00315-8. NPJ Breast Cancer. 2021. PMID: 34433815 Free PMC article.
A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer.
Polak P, Kim J, Braunstein LZ, Karlic R, Haradhavala NJ, Tiao G, Rosebrock D, Livitz D, Kübler K, Mouw KW, Kamburov A, Maruvka YE, Leshchiner I, Lander ES, Golub TR, Zick A, Orthwein A, Lawrence MS, Batra RN, Caldas C, Haber DA, Laird PW, Shen H, Ellisen LW, D'Andrea AD, Chanock SJ, Foulkes WD, Getz G. Polak P, et al. Nat Genet. 2017 Oct;49(10):1476-1486. doi: 10.1038/ng.3934. Epub 2017 Aug 21. Nat Genet. 2017. PMID: 28825726 Free PMC article.
Monogenic Diseases of DNA Repair.
Rivera B, Polak P, Foulkes WD. Rivera B, et al. Among authors: polak p. N Engl J Med. 2018 Feb 1;378(5):491. doi: 10.1056/NEJMc1716072. N Engl J Med. 2018. PMID: 29394477 No abstract available.
Bilateral Tumors - Inherited or Acquired?
Foulkes WD, Polak P. Foulkes WD, et al. Among authors: polak p. N Engl J Med. 2020 Jul 16;383(3):280-282. doi: 10.1056/NEJMcibr2007784. N Engl J Med. 2020. PMID: 32668120 No abstract available.
A Preclinical Trial and Molecularly Annotated Patient Cohort Identify Predictive Biomarkers in Homologous Recombination-deficient Pancreatic Cancer.
Wang Y, Park JYP, Pacis A, Denroche RE, Jang GH, Zhang A, Cuggia A, Domecq C, Monlong J, Raitses-Gurevich M, Grant RC, Borgida A, Holter S, Stossel C, Bu S, Masoomian M, Lungu IM, Bartlett JMS, Wilson JM, Gao ZH, Riazalhosseini Y, Asselah J, Bouganim N, Cabrera T, Boucher LM, Valenti D, Biagi J, Greenwood CMT, Polak P, Foulkes WD, Golan T, O'Kane GM, Fischer SE, Knox JJ, Gallinger S, Zogopoulos G. Wang Y, et al. Among authors: polak p. Clin Cancer Res. 2020 Oct 15;26(20):5462-5476. doi: 10.1158/1078-0432.CCR-20-1439. Epub 2020 Aug 14. Clin Cancer Res. 2020. PMID: 32816949
361 results