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Page 1
Stereoselective Activity of 1-Propargyl-4-styrylpiperidine-like Analogues That Can Discriminate between Monoamine Oxidase Isoforms A and B.
Knez D, Colettis N, Iacovino LG, Sova M, Pišlar A, Konc J, Lešnik S, Higgs J, Kamecki F, Mangialavori I, Dolšak A, Žakelj S, Trontelj J, Kos J, Binda C, Marder M, Gobec S. Knez D, et al. Among authors: iacovino lg. J Med Chem. 2020 Feb 13;63(3):1361-1387. doi: 10.1021/acs.jmedchem.9b01886. Epub 2020 Jan 22. J Med Chem. 2020. PMID: 31917923 Free PMC article.
Promising Non-cytotoxic Monosubstituted Chalcones to Target Monoamine Oxidase-B.
Iacovino LG, Pinzi L, Facchetti G, Bortolini B, Christodoulou MS, Binda C, Rastelli G, Rimoldi I, Passarella D, Di Paolo ML, Dalla Via L. Iacovino LG, et al. ACS Med Chem Lett. 2021 Jun 14;12(7):1151-1158. doi: 10.1021/acsmedchemlett.1c00238. eCollection 2021 Jul 8. ACS Med Chem Lett. 2021. PMID: 34262643 Free PMC article.
Assessment of Tractable Cysteines for Covalent Targeting by Screening Covalent Fragments.
Petri L, Ábrányi-Balogh P, Tímea I, Pálfy G, Perczel A, Knez D, Hrast M, Gobec M, Sosič I, Nyíri K, Vértessy BG, Jänsch N, Desczyk C, Meyer-Almes FJ, Ogris I, Golič Grdadolnik S, Iacovino LG, Binda C, Gobec S, Keserű GM. Petri L, et al. Among authors: iacovino lg. Chembiochem. 2021 Feb 15;22(4):743-753. doi: 10.1002/cbic.202000700. Epub 2020 Nov 9. Chembiochem. 2021. PMID: 33030752
Transcription-replication conflicts underlie sensitivity to PARP inhibitors.
Petropoulos M, Karamichali A, Rossetti GG, Freudenmann A, Iacovino LG, Dionellis VS, Sotiriou SK, Halazonetis TD. Petropoulos M, et al. Among authors: iacovino lg. Nature. 2024 Apr;628(8007):433-441. doi: 10.1038/s41586-024-07217-2. Epub 2024 Mar 20. Nature. 2024. PMID: 38509368 Free PMC article.