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Page 1
Targeted IgMs agonize ocular targets with extended vitreal exposure.
Chen Y, Paluch M, Zorn JA, Rajan S, Leonard B, Estevez A, Brady J, Chiu H, Phung W, Famili A, Yan M, Ciferri C, Matsumoto ML, Lazar GA, Crowell S, Hass P, Agard NJ. Chen Y, et al. Among authors: agard nj. MAbs. 2020 Jan-Dec;12(1):1818436. doi: 10.1080/19420862.2020.1818436. MAbs. 2020. PMID: 32936727 Free PMC article.
Antibody targeting of E3 ubiquitin ligases for receptor degradation.
Marei H, Tsai WK, Kee YS, Ruiz K, He J, Cox C, Sun T, Penikalapati S, Dwivedi P, Choi M, Kan D, Saenz-Lopez P, Dorighi K, Zhang P, Kschonsak YT, Kljavin N, Amin D, Kim I, Mancini AG, Nguyen T, Wang C, Janezic E, Doan A, Mai E, Xi H, Gu C, Heinlein M, Biehs B, Wu J, Lehoux I, Harris S, Comps-Agrar L, Seshasayee D, de Sauvage FJ, Grimmer M, Li J, Agard NJ, de Sousa E Melo F. Marei H, et al. Among authors: agard nj. Nature. 2022 Oct;610(7930):182-189. doi: 10.1038/s41586-022-05235-6. Epub 2022 Sep 21. Nature. 2022. PMID: 36131013 Free PMC article.
Translatability of In Vitro Stress for Predicting Deamidation and Oxidation Biotransformation on Biotherapeutics.
Chu PY, Wang H, Ross E, Stephens N, Zhang HM, Andersen N, Chan W, Shivva V, Crowell SR, Spiess C, Holder PG, Agard NJ, Ji C, Chen J, Sreedhara A, Wang J, Wu C, Liu Y, Tran JC. Chu PY, et al. Among authors: agard nj. Anal Chem. 2023 Dec 12;95(49):17957-17961. doi: 10.1021/acs.analchem.3c02133. Epub 2023 Nov 30. Anal Chem. 2023. PMID: 38084380
Direct Tie2 Agonists Stabilize Vasculature for the Treatment of Diabetic Macular Edema.
Agard NJ, Zhang G, Ridgeway J, Dicara DM, Chu PY, Ohri R, Sanowar S, Vernes JM, Chi H, Zhang J, Holz E, Paluch M, He G, Benson Y, Zhang J, Chan P, Tang N, Javale P, Wilson B, Barrett K, Rowntree RK, Hang J, Meng YG, Hass P, Fuh G, Piskol R, Bantseev V, Loyet KM, Tran JC, Wu C, Indjeian VB, Shivva V, Yan M. Agard NJ, et al. Transl Vis Sci Technol. 2022 Oct 3;11(10):27. doi: 10.1167/tvst.11.10.27. Transl Vis Sci Technol. 2022. PMID: 36255358 Free PMC article.
Preclinical optimization of Ly6E-targeted ADCs for increased durability and efficacy of anti-tumor response.
Dela Cruz Chuh J, Go M, Chen Y, Guo J, Rafidi H, Mandikian D, Sun Y, Lin Z, Schneider K, Zhang P, Vij R, Sharpnack D, Chan P, de la Cruz C, Sadowsky J, Seshasayee D, Koerber JT, Pillow TH, Phillips GD, Rowntree RK, Boswell CA, Kozak KR, Polson AG, Polakis P, Yu SF, Dragovich PS, Agard NJ. Dela Cruz Chuh J, et al. Among authors: agard nj. MAbs. 2021 Jan-Dec;13(1):1862452. doi: 10.1080/19420862.2020.1862452. MAbs. 2021. PMID: 33382956 Free PMC article.
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