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Page 1
Virally programmed extracellular vesicles sensitize cancer cells to oncolytic virus and small molecule therapy.
Wedge ME, Jennings VA, Crupi MJF, Poutou J, Jamieson T, Pelin A, Pugliese G, de Souza CT, Petryk J, Laight BJ, Boileau M, Taha Z, Alluqmani N, McKay HE, Pikor L, Khan ST, Azad T, Rezaei R, Austin B, He X, Mansfield D, Rose E, Brown EEF, Crawford N, Alkayyal A, Surendran A, Singaravelu R, Roy DG, Migneco G, McSweeney B, Cottee ML, Jacobus EJ, Keller BA, Yamaguchi TN, Boutros PC, Geoffrion M, Rayner KJ, Chatterjee A, Auer RC, Diallo JS, Gibbings D, tenOever BR, Melcher A, Bell JC, Ilkow CS. Wedge ME, et al. Among authors: rayner kj. Nat Commun. 2022 Apr 7;13(1):1898. doi: 10.1038/s41467-022-29526-8. Nat Commun. 2022. PMID: 35393414 Free PMC article.
Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity.
Ramkhelawon B, Hennessy EJ, Ménager M, Ray TD, Sheedy FJ, Hutchison S, Wanschel A, Oldebeken S, Geoffrion M, Spiro W, Miller G, McPherson R, Rayner KJ, Moore KJ. Ramkhelawon B, et al. Among authors: rayner kj. Nat Med. 2014 Apr;20(4):377-84. doi: 10.1038/nm.3467. Epub 2014 Mar 2. Nat Med. 2014. PMID: 24584118 Free PMC article.
Macrophage Mitochondrial Energy Status Regulates Cholesterol Efflux and Is Enhanced by Anti-miR33 in Atherosclerosis.
Karunakaran D, Thrush AB, Nguyen MA, Richards L, Geoffrion M, Singaravelu R, Ramphos E, Shangari P, Ouimet M, Pezacki JP, Moore KJ, Perisic L, Maegdefessel L, Hedin U, Harper ME, Rayner KJ. Karunakaran D, et al. Among authors: rayner kj. Circ Res. 2015 Jul 17;117(3):266-78. doi: 10.1161/CIRCRESAHA.117.305624. Epub 2015 May 22. Circ Res. 2015. PMID: 26002865 Free PMC article.
MicroRNAs regulate the immunometabolic response to viral infection in the liver.
Singaravelu R, O'Hara S, Jones DM, Chen R, Taylor NG, Srinivasan P, Quan C, Roy DG, Steenbergen RH, Kumar A, Lyn RK, Özcelik D, Rouleau Y, Nguyen MA, Rayner KJ, Hobman TC, Tyrrell DL, Russell RS, Pezacki JP. Singaravelu R, et al. Among authors: rayner kj. Nat Chem Biol. 2015 Dec;11(12):988-93. doi: 10.1038/nchembio.1940. Epub 2015 Oct 19. Nat Chem Biol. 2015. PMID: 26479438
Loss of MLKL (Mixed Lineage Kinase Domain-Like Protein) Decreases Necrotic Core but Increases Macrophage Lipid Accumulation in Atherosclerosis.
Rasheed A, Robichaud S, Nguyen MA, Geoffrion M, Wyatt H, Cottee ML, Dennison T, Pietrangelo A, Lee R, Lagace TA, Ouimet M, Rayner KJ. Rasheed A, et al. Among authors: rayner kj. Arterioscler Thromb Vasc Biol. 2020 May;40(5):1155-1167. doi: 10.1161/ATVBAHA.119.313640. Epub 2020 Mar 26. Arterioscler Thromb Vasc Biol. 2020. PMID: 32212851 Free article.
RIPK1 gene variants associate with obesity in humans and can be therapeutically silenced to reduce obesity in mice.
Karunakaran D, Turner AW, Duchez AC, Soubeyrand S, Rasheed A, Smyth D, Cook DP, Nikpay M, Kandiah JW, Pan C, Geoffrion M, Lee R, Boytard L, Wyatt H, Nguyen MA, Lau P, Laakso M, Ramkhelawon B, Alvarez M, Pietiläinen KH, Pajukanta P, Vanderhyden BC, Liu P, Berger SB, Gough PJ, Bertin J, Harper ME, Lusis AJ, McPherson R, Rayner KJ. Karunakaran D, et al. Among authors: rayner kj. Nat Metab. 2020 Oct;2(10):1113-1125. doi: 10.1038/s42255-020-00279-2. Epub 2020 Sep 28. Nat Metab. 2020. PMID: 32989316 Free PMC article.
100 results