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ALS-associated KIF5A mutations abolish autoinhibition resulting in a toxic gain of function.
Baron DM, Fenton AR, Saez-Atienzar S, Giampetruzzi A, Sreeram A, Shankaracharya, Keagle PJ, Doocy VR, Smith NJ, Danielson EW, Andresano M, McCormack MC, Garcia J, Bercier V, Van Den Bosch L, Brent JR, Fallini C, Traynor BJ, Holzbaur ELF, Landers JE. Baron DM, et al. Among authors: holzbaur elf. Cell Rep. 2022 Apr 5;39(1):110598. doi: 10.1016/j.celrep.2022.110598. Cell Rep. 2022. PMID: 35385738 Free PMC article.
Axonal transport and neurodegenerative disease.
Chevalier-Larsen E, Holzbaur EL. Chevalier-Larsen E, et al. Biochim Biophys Acta. 2006 Nov-Dec;1762(11-12):1094-108. doi: 10.1016/j.bbadis.2006.04.002. Epub 2006 Apr 19. Biochim Biophys Acta. 2006. PMID: 16730956 Free article. Review.
SnapShot: axonal transport.
Twelvetrees A, Hendricks AG, Holzbaur EL. Twelvetrees A, et al. Cell. 2012 May 11;149(4):950-950.e1. doi: 10.1016/j.cell.2012.05.001. Cell. 2012. PMID: 22579292 Free article. No abstract available.
Autophagy and mitophagy in ALS.
Evans CS, Holzbaur ELF. Evans CS, et al. Among authors: holzbaur elf. Neurobiol Dis. 2019 Feb;122:35-40. doi: 10.1016/j.nbd.2018.07.005. Epub 2018 Jul 5. Neurobiol Dis. 2019. PMID: 29981842 Free PMC article. Review.
Mitochondrial dynamics: Shaping and remodeling an organelle network.
Fenton AR, Jongens TA, Holzbaur ELF. Fenton AR, et al. Among authors: holzbaur elf. Curr Opin Cell Biol. 2021 Feb;68:28-36. doi: 10.1016/j.ceb.2020.08.014. Epub 2020 Sep 19. Curr Opin Cell Biol. 2021. PMID: 32961383 Free PMC article. Review.
218 results