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The hypoxic epicardial and subepicardial microenvironment.
Kocabas F, Mahmoud AI, Sosic D, Porrello ER, Chen R, Garcia JA, DeBerardinis RJ, Sadek HA. Kocabas F, et al. Among authors: chen r. J Cardiovasc Transl Res. 2012 Oct;5(5):654-65. doi: 10.1007/s12265-012-9366-7. Epub 2012 May 8. J Cardiovasc Transl Res. 2012. PMID: 22566269
Allosteric inhibition of hypoxia inducible factor-2 with small molecules.
Scheuermann TH, Li Q, Ma HW, Key J, Zhang L, Chen R, Garcia JA, Naidoo J, Longgood J, Frantz DE, Tambar UK, Gardner KH, Bruick RK. Scheuermann TH, et al. Among authors: chen r. Nat Chem Biol. 2013 Apr;9(4):271-6. doi: 10.1038/nchembio.1185. Epub 2013 Feb 24. Nat Chem Biol. 2013. PMID: 23434853 Free PMC article.
A niche-derived nonribosomal peptide triggers planarian sexual development.
Issigonis M, Browder KL, Chen R, Collins JJ 3rd, Newmark PA. Issigonis M, et al. Among authors: chen r. Proc Natl Acad Sci U S A. 2024 Jun 25;121(26):e2321349121. doi: 10.1073/pnas.2321349121. Epub 2024 Jun 18. Proc Natl Acad Sci U S A. 2024. PMID: 38889152 Free PMC article.
The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response.
Puente BN, Kimura W, Muralidhar SA, Moon J, Amatruda JF, Phelps KL, Grinsfelder D, Rothermel BA, Chen R, Garcia JA, Santos CX, Thet S, Mori E, Kinter MT, Rindler PM, Zacchigna S, Mukherjee S, Chen DJ, Mahmoud AI, Giacca M, Rabinovitch PS, Aroumougame A, Shah AM, Szweda LI, Sadek HA. Puente BN, et al. Among authors: chen r, chen dj. Cell. 2014 Apr 24;157(3):565-79. doi: 10.1016/j.cell.2014.03.032. Cell. 2014. PMID: 24766806 Free PMC article.
An acetate switch regulates stress erythropoiesis.
Xu M, Nagati JS, Xie J, Li J, Walters H, Moon YA, Gerard RD, Huang CL, Comerford SA, Hammer RE, Horton JD, Chen R, Garcia JA. Xu M, et al. Among authors: chen r. Nat Med. 2014 Sep;20(9):1018-26. doi: 10.1038/nm.3587. Epub 2014 Aug 10. Nat Med. 2014. PMID: 25108527 Free PMC article.
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