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Potent cyclic monomeric and dimeric peptide inhibitors of VLA-4 (alpha4beta1 integrin)-mediated cell adhesion based on the Ile-Leu-Asp-Val tetrapeptide.
Dutta AS, Crowther M, Gormley JJ, Hassall L, Hayward CF, Gellert PR, Kittlety RS, Alcock PJ, Jamieson A, Moores JM, Rees A, Wood LJ, Reilly CF, Haworth D. Dutta AS, et al. Among authors: gellert pr. J Pept Sci. 2000 Jul;6(7):321-41. doi: 10.1002/1099-1387(200007)6:7<321::AID-PSC259>3.0.CO;2-A. J Pept Sci. 2000. PMID: 10946997
In silico modelling of drug-polymer interactions for pharmaceutical formulations.
Ahmad S, Johnston BF, Mackay SP, Schatzlein AG, Gellert P, Sengupta D, Uchegbu IF. Ahmad S, et al. Among authors: gellert p. J R Soc Interface. 2010 Aug 6;7 Suppl 4(Suppl 4):S423-33. doi: 10.1098/rsif.2010.0190.focus. Epub 2010 Jun 2. J R Soc Interface. 2010. PMID: 20519214 Free PMC article.
Potent cyclic peptide inhibitors of VLA-4 (alpha4beta1 integrin)-mediated cell adhesion. Discovery of compounds like cyclo(MePhe-Leu-Asp-Val-D-Arg-D-Arg) (ZD7349) compatible with depot formulation.
Dutta AS, Gormley JJ, Coath M, Hassall L, Hayward CF, Gellert PR, Kittlety RS, Alcock PJ, Ferguson R, Halterman T, Jamieson A, Moors JA, Moores JM, Rees A, Wood LJ, Reilly CF, Haworth D. Dutta AS, et al. Among authors: gellert pr. J Pept Sci. 2000 Aug;6(8):398-412. doi: 10.1002/1099-1387(200008)6:8<398::AID-PSC270>3.0.CO;2-1. J Pept Sci. 2000. PMID: 10969869
154 results