Littler DR - Search Results

1

Crystal structures of pertussis toxin with NAD⁺ and analogs provide structural insights into the mechanism of its cytosolic ADP-ribosylation activity.

Sakari M, Tran MT, Rossjohn J, Pulliainen AT, Beddoe T, Littler DR. Sakari M, et al. Among authors: littler dr. J Biol Chem. 2022 May;298(5):101892. doi: 10.1016/j.jbc.2022.101892. Epub 2022 Apr 1. J Biol Chem. 2022. PMID: 35378130 Free PMC article.

2

Polo-box domains confer target specificity to the Polo-like kinase family.

van de Weerdt BC, Littler DR, Klompmaker R, Huseinovic A, Fish A, Perrakis A, Medema RH. van de Weerdt BC, et al. Among authors: littler dr. Biochim Biophys Acta. 2008 Jun;1783(6):1015-22. doi: 10.1016/j.bbamcr.2008.02.019. Epub 2008 Mar 5. Biochim Biophys Acta. 2008. PMID: 18359294 Free article.

3

Cloning, expression, purification and preliminary X-ray diffraction studies of a mycobacterial protein implicated in bacterial survival in macrophages.

Shahine AE, Chan PY, Littler D, Vivian J, Brammananth R, Crellin PK, Coppel RL, Rossjohn J, Beddoe T. Shahine AE, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 May 1;69(Pt 5):566-9. doi: 10.1107/S1744309113010427. Epub 2013 Apr 30. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013. PMID: 23695579 Free PMC article.

4

Cloning, expression, purification and preliminary X-ray diffraction studies of a novel AB₅ toxin.

Ng N, Littler D, Le Nours J, Paton AW, Paton JC, Rossjohn J, Beddoe T. Ng N, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Aug;69(Pt 8):912-5. doi: 10.1107/S1744309113018927. Epub 2013 Jul 27. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013. PMID: 23908042 Free PMC article.

5

EcxAB is a founding member of a new family of metalloprotease AB5 toxins with a hybrid cholera-like B subunit.

Ng NM, Littler DR, Paton AW, Le Nours J, Rossjohn J, Paton JC, Beddoe T. Ng NM, et al. Among authors: littler dr. Structure. 2013 Nov 5;21(11):2003-13. doi: 10.1016/j.str.2013.08.024. Epub 2013 Oct 3. Structure. 2013. PMID: 24095060 Free article.

6

The structure of the cytomegalovirus-encoded m04 glycoprotein, a prototypical member of the m02 family of immunoevasins.

Berry R, Vivian JP, Deuss FA, Balaji GR, Saunders PM, Lin J, Littler DR, Brooks AG, Rossjohn J. Berry R, et al. Among authors: littler dr. J Biol Chem. 2014 Aug 22;289(34):23753-63. doi: 10.1074/jbc.M114.584128. Epub 2014 Jun 30. J Biol Chem. 2014. PMID: 24982419 Free PMC article.

7

A structural and functional investigation of a novel protein from Mycobacterium smegmatis implicated in mycobacterial macrophage survivability.

Shahine A, Littler D, Brammananath R, Chan PY, Crellin PK, Coppel RL, Rossjohn J, Beddoe T. Shahine A, et al. Acta Crystallogr D Biol Crystallogr. 2014 Sep;70(Pt 9):2264-76. doi: 10.1107/S139900471401092X. Epub 2014 Aug 23. Acta Crystallogr D Biol Crystallogr. 2014. PMID: 25195741

8

Cloning, expression, purification and crystallographic studies of galectin-11 from domestic sheep (Ovis aries).

Sakthivel D, Littler D, Shahine A, Troy S, Johnson M, Rossjohn J, Piedrafita D, Beddoe T. Sakthivel D, et al. Acta Crystallogr F Struct Biol Commun. 2015 Aug;71(Pt 8):993-7. doi: 10.1107/S2053230X15010195. Epub 2015 Jul 28. Acta Crystallogr F Struct Biol Commun. 2015. PMID: 26249688 Free PMC article.

9

Disrupting the Allosteric Interaction between the Plasmodium falciparum cAMP-dependent Kinase and Its Regulatory Subunit.

Littler DR, Bullen HE, Harvey KL, Beddoe T, Crabb BS, Rossjohn J, Gilson PR. Littler DR, et al. J Biol Chem. 2016 Dec 2;291(49):25375-25386. doi: 10.1074/jbc.M116.750174. Epub 2016 Oct 13. J Biol Chem. 2016. PMID: 27738107 Free PMC article.

10

Crystal structure of fuculose aldolase from the Antarctic psychrophilic yeast Glaciozyma antarctica PI12.

Jaafar NR, Littler D, Beddoe T, Rossjohn J, Illias RM, Mahadi NM, Mackeen MM, Murad AM, Abu Bakar FD. Jaafar NR, et al. Acta Crystallogr F Struct Biol Commun. 2016 Nov 1;72(Pt 11):831-839. doi: 10.1107/S2053230X16015612. Epub 2016 Oct 27. Acta Crystallogr F Struct Biol Commun. 2016. PMID: 27827354 Free PMC article.

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