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A novel dual mode-of-action anti-hyperalgesic compound in rats which is neuroprotective and promotes neuroregeneration.
Bloms-Funke P, Schumacher M, Liu S, Su D, Li J, Liere P, Rupprecht R, Nothdurfter C, Bahrenberg G, Christoph T, Habermann C, Kneip C, Schröder W, Tzschentke TM, Saunders D. Bloms-Funke P, et al. Among authors: schumacher m. Eur J Pharmacol. 2022 May 15;923:174935. doi: 10.1016/j.ejphar.2022.174935. Epub 2022 Apr 2. Eur J Pharmacol. 2022. PMID: 35378102
SSR180575 (7-chloro-N,N,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide), a peripheral benzodiazepine receptor ligand, promotes neuronal survival and repair.
Ferzaz B, Brault E, Bourliaud G, Robert JP, Poughon G, Claustre Y, Marguet F, Liere P, Schumacher M, Nowicki JP, Fournier J, Marabout B, Sevrin M, George P, Soubrie P, Benavides J, Scatton B. Ferzaz B, et al. Among authors: schumacher m. J Pharmacol Exp Ther. 2002 Jun;301(3):1067-78. doi: 10.1124/jpet.301.3.1067. J Pharmacol Exp Ther. 2002. PMID: 12023539
3 Beta-hydroxysteroid dehydrogenase expression in rat spinal cord.
Coirini H, Gouézou M, Liere P, Delespierre B, Pianos A, Eychenne B, Schumacher M, Guennoun R. Coirini H, et al. Among authors: schumacher m. Neuroscience. 2002;113(4):883-91. doi: 10.1016/s0306-4522(02)00224-5. Neuroscience. 2002. PMID: 12182894
In vitro metabolism of dehydroepiandrosterone (DHEA) to 7alpha-hydroxy-DHEA and Delta5-androstene-3beta,17beta-diol in specific regions of the aging brain from Alzheimer's and non-demented patients.
Weill-Engerer S, David JP, Sazdovitch V, Liere P, Schumacher M, Delacourte A, Baulieu EE, Akwa Y. Weill-Engerer S, et al. Among authors: schumacher m. Brain Res. 2003 Apr 18;969(1-2):117-25. doi: 10.1016/s0006-8993(03)02288-1. Brain Res. 2003. PMID: 12676372
2,021 results