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Nanoparticle targeting to the endothelium during normothermic machine perfusion of human kidneys.
Tietjen GT, Hosgood SA, DiRito J, Cui J, Deep D, Song E, Kraehling JR, Piotrowski-Daspit AS, Kirkiles-Smith NC, Al-Lamki R, Thiru S, Bradley JA, Saeb-Parsy K, Bradley JR, Nicholson ML, Saltzman WM, Pober JS. Tietjen GT, et al. Sci Transl Med. 2017 Nov 29;9(418):eaam6764. doi: 10.1126/scitranslmed.aam6764. Sci Transl Med. 2017. PMID: 29187644 Free PMC article.
Poly(amine-co-ester) nanoparticles for effective Nogo-B knockdown in the liver.
Cui J, Piotrowski-Daspit AS, Zhang J, Shao M, Bracaglia LG, Utsumi T, Seo YE, DiRito J, Song E, Wu C, Inada A, Tietjen GT, Pober JS, Iwakiri Y, Saltzman WM. Cui J, et al. Among authors: tietjen gt. J Control Release. 2019 Jun 28;304:259-267. doi: 10.1016/j.jconrel.2019.04.044. Epub 2019 May 1. J Control Release. 2019. PMID: 31054286 Free PMC article.
ZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-κB via phosphoinosotide remodeling of endosomes.
Fang C, Manes TD, Liu L, Liu K, Qin L, Li G, Tobiasova Z, Kirkiles-Smith NC, Patel M, Merola J, Fu W, Liu R, Xie C, Tietjen GT, Nigrovic PA, Tellides G, Pober JS, Jane-Wit D. Fang C, et al. Among authors: tietjen gt. Nat Commun. 2019 May 21;10(1):2247. doi: 10.1038/s41467-019-10041-2. Nat Commun. 2019. PMID: 31113953 Free PMC article.
Progenitor-derived human endothelial cells evade alloimmunity by CRISPR/Cas9-mediated complete ablation of MHC expression.
Merola J, Reschke M, Pierce RW, Qin L, Spindler S, Baltazar T, Manes TD, Lopez-Giraldez F, Li G, Bracaglia LG, Xie C, Kirkiles-Smith N, Saltzman WM, Tietjen GT, Tellides G, Pober JS. Merola J, et al. Among authors: tietjen gt. JCI Insight. 2019 Oct 17;4(20):e129739. doi: 10.1172/jci.insight.129739. JCI Insight. 2019. PMID: 31527312 Free PMC article.
34 results