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Inhibition of SARS-CoV-2 replication in the lung with siRNA/VIPER polyplexes.
Baldassi D, Ambike S, Feuerherd M, Cheng CC, Peeler DJ, Feldmann DP, Porras-Gonzalez DL, Wei X, Keller LA, Kneidinger N, Stoleriu MG, Popp A, Burgstaller G, Pun SH, Michler T, Merkel OM. Baldassi D, et al. Among authors: michler t. J Control Release. 2022 May;345:661-674. doi: 10.1016/j.jconrel.2022.03.051. Epub 2022 Mar 29. J Control Release. 2022. PMID: 35364120 Free PMC article.
Targeting genomic SARS-CoV-2 RNA with siRNAs allows efficient inhibition of viral replication and spread.
Ambike S, Cheng CC, Feuerherd M, Velkov S, Baldassi D, Afridi SQ, Porras-Gonzalez D, Wei X, Hagen P, Kneidinger N, Stoleriu MG, Grass V, Burgstaller G, Pichlmair A, Merkel OM, Ko C, Michler T. Ambike S, et al. Among authors: michler t. Nucleic Acids Res. 2022 Jan 11;50(1):333-349. doi: 10.1093/nar/gkab1248. Nucleic Acids Res. 2022. PMID: 34928377 Free PMC article.
Knockdown of Virus Antigen Expression Increases Therapeutic Vaccine Efficacy in High-Titer Hepatitis B Virus Carrier Mice.
Michler T, Kosinska AD, Festag J, Bunse T, Su J, Ringelhan M, Imhof H, Grimm D, Steiger K, Mogler C, Heikenwalder M, Michel ML, Guzman CA, Milstein S, Sepp-Lorenzino L, Knolle P, Protzer U. Michler T, et al. Gastroenterology. 2020 May;158(6):1762-1775.e9. doi: 10.1053/j.gastro.2020.01.032. Epub 2020 Jan 28. Gastroenterology. 2020. PMID: 32001321
Data, Reagents, Assays and Merits of Proteomics for SARS-CoV-2 Research and Testing.
Zecha J, Lee CY, Bayer FP, Meng C, Grass V, Zerweck J, Schnatbaum K, Michler T, Pichlmair A, Ludwig C, Kuster B. Zecha J, et al. Among authors: michler t. Mol Cell Proteomics. 2020 Sep;19(9):1503-1522. doi: 10.1074/mcp.RA120.002164. Epub 2020 Jun 26. Mol Cell Proteomics. 2020. PMID: 32591346 Free PMC article.
Implementation and User Satisfaction of a Comprehensive Telemedicine Approach for SARS-CoV-2 Self-Sampling: Monocentric, Prospective, Interventional, Open-Label, Controlled, Two-Arm Feasibility Study.
Voit F, Erber J, Egert-Schwender S, Hanselmann M, Laxy M, Kehl V, Hoffmann D, Jeske SD, Michler T, Protzer U, Kohlmayer F, Schmid RM, Spinner CD, Weidlich S. Voit F, et al. Among authors: michler t. JMIR Form Res. 2024 Dec 11;8:e57608. doi: 10.2196/57608. JMIR Form Res. 2024. PMID: 39661941 Free PMC article. Clinical Trial.
New pharmacological strategies to fight enveloped viruses.
Wisskirchen K, Lucifora J, Michler T, Protzer U. Wisskirchen K, et al. Among authors: michler t. Trends Pharmacol Sci. 2014 Sep;35(9):470-8. doi: 10.1016/j.tips.2014.06.004. Epub 2014 Aug 6. Trends Pharmacol Sci. 2014. PMID: 25108320 Free PMC article. Review.
Novel viral and host targets to cure hepatitis B.
Ko C, Michler T, Protzer U. Ko C, et al. Among authors: michler t. Curr Opin Virol. 2017 Jun;24:38-45. doi: 10.1016/j.coviro.2017.03.019. Epub 2017 Apr 20. Curr Opin Virol. 2017. PMID: 28433762 Review.
25 results