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Mutated Toll-like receptor 9 increases Alzheimer's disease risk by compromising innate immunity protection.
Cacace R, Zhou L, Hendrickx Van de Craen E, Buist A, Hoogmartens J, Sieben A, Cras P, Vandenberghe R, De Deyn PP, Oehlrich D, De Bondt A, Engelborghs S, Moechars D, Van Broeckhoven C. Cacace R, et al. Among authors: hendrickx van de craen e. Mol Psychiatry. 2023 Dec;28(12):5380-5389. doi: 10.1038/s41380-023-02166-0. Epub 2023 Jul 11. Mol Psychiatry. 2023. PMID: 37433968 Free PMC article.
Patients carrying the mutation p.R406W in MAPT present with non-conforming phenotypic spectrum.
Gossye H, Van Mossevelde S, Sieben A, Bjerke M, Hendrickx Van de Craen E, van der Zee J, De Deyn PP, De Bleecker J, Versijpt J, van den Ende J, Deryck O, Bourgeois P, Bier JC, Goethals M, Vandenberghe R, Engelborghs S, Van Broeckhoven C. Gossye H, et al. Among authors: hendrickx van de craen e. Brain. 2023 Apr 19;146(4):1624-1636. doi: 10.1093/brain/awac362. Brain. 2023. PMID: 36171642 Free PMC article.