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Page 1
A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation, and reduced inflammation in obstructive airway diseases.
Ghigo A, Murabito A, Sala V, Pisano AR, Bertolini S, Gianotti A, Caci E, Montresor A, Premchandar A, Pirozzi F, Ren K, Della Sala A, Mergiotti M, Richter W, de Poel E, Matthey M, Caldrer S, Cardone RA, Civiletti F, Costamagna A, Quinney NL, Butnarasu C, Visentin S, Ruggiero MR, Baroni S, Crich SG, Ramel D, Laffargue M, Tocchetti CG, Levi R, Conti M, Lu XY, Melotti P, Sorio C, De Rose V, Facchinetti F, Fanelli V, Wenzel D, Fleischmann BK, Mall MA, Beekman J, Laudanna C, Gentzsch M, Lukacs GL, Pedemonte N, Hirsch E. Ghigo A, et al. Among authors: bertolini s. Sci Transl Med. 2022 Mar 30;14(638):eabl6328. doi: 10.1126/scitranslmed.abl6328. Epub 2022 Mar 30. Sci Transl Med. 2022. PMID: 35353541 Free PMC article.
Cigarette smoke and its component acrolein augment IL-8/CXCL8 mRNA stability via p38 MAPK/MK2 signaling in human pulmonary cells.
Moretto N, Bertolini S, Iadicicco C, Marchini G, Kaur M, Volpi G, Patacchini R, Singh D, Facchinetti F. Moretto N, et al. Among authors: bertolini s. Am J Physiol Lung Cell Mol Physiol. 2012 Nov 15;303(10):L929-38. doi: 10.1152/ajplung.00046.2012. Epub 2012 Sep 14. Am J Physiol Lung Cell Mol Physiol. 2012. PMID: 22983351 Free article. Clinical Trial.
Atropisomerism and Conformational Equilibria: Impact on PI3Kδ Inhibition of 2-((6-Amino-9H-purin-9-yl)methyl)-5-methyl-3-(o-tolyl)quinazolin-4(3H)-one (IC87114) and Its Conformationally Restricted Analogs.
Lodola A, Bertolini S, Biagetti M, Capacchi S, Facchinetti F, Gallo PM, Pappani A, Mor M, Pala D, Rivara S, Visentini F, Corsi M, Capelli AM. Lodola A, et al. Among authors: bertolini s. J Med Chem. 2017 May 25;60(10):4304-4315. doi: 10.1021/acs.jmedchem.7b00247. Epub 2017 May 15. J Med Chem. 2017. PMID: 28489362
Discovery of CHF-6523, an Inhaled Selective PI3Kδ Inhibitor for the Treatment of Chronic Obstructive Pulmonary Disease.
Bruno P, Pala D, Micoli A, Corsi M, Accetta A, Carzaniga L, Ronchi P, Fiorelli C, Formica M, Pizzirani D, Mazzucato R, Guariento S, Bertolini S, Martucci C, Allen AD, Mileo V, Capacchi S, Gallo PM, Fioni A, Xanxo Fernandez S, Villetti G, Puccini P, Civelli M, Guala M, Retini M, Martinelli P, Visentini F, Pavoni V, Daldosso M, Fontana S, Biagetti M, Capelli AM. Bruno P, et al. Among authors: bertolini s. J Med Chem. 2024 Dec 5. doi: 10.1021/acs.jmedchem.4c02062. Online ahead of print. J Med Chem. 2024. PMID: 39635891
Consensus document on diagnosis and management of familial hypercholesterolemia from the Italian Society for the Study of Atherosclerosis (SISA).
Tarugi P, Bertolini S, Calandra S, Arca M, Angelico F, Casula M, Cefalù AB, D'Erasmo L, Fortunato G, Perrone-Filardi P, Rubba P, Suppressa P, Averna M, Catapano AL. Tarugi P, et al. Among authors: bertolini s. Nutr Metab Cardiovasc Dis. 2024 Aug;34(8):1819-1836. doi: 10.1016/j.numecd.2024.05.002. Epub 2024 May 7. Nutr Metab Cardiovasc Dis. 2024. PMID: 38871496 Review.
Contemporary lipid-lowering management and risk of cardiovascular events in homozygous familial hypercholesterolaemia: insights from the Italian LIPIGEN Registry.
D'Erasmo L, Bini S, Casula M, Gazzotti M, Bertolini S, Calandra S, Tarugi P, Averna M, Iannuzzo G, Fortunato G, Catapano AL, Arca M; LIPIGEN HoFH group. D'Erasmo L, et al. Among authors: bertolini s. Eur J Prev Cardiol. 2024 Jun 3;31(8):1038-1047. doi: 10.1093/eurjpc/zwae036. Eur J Prev Cardiol. 2024. PMID: 38374534
307 results