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Microfluidic Antibody Affinity Profiling Reveals the Role of Memory Reactivation and Cross-Reactivity in the Defense Against SARS-CoV-2.
Denninger V, Xu CK, Meisl G, Morgunov AS, Fiedler S, Ilsley A, Emmenegger M, Malik AY, Piziorska MA, Schneider MM, Devenish SRA, Kosmoliaptsis V, Aguzzi A, Fiegler H, Knowles TPJ. Denninger V, et al. Among authors: aguzzi a. ACS Infect Dis. 2022 Apr 8;8(4):790-799. doi: 10.1021/acsinfecdis.1c00486. Epub 2022 Mar 30. ACS Infect Dis. 2022. PMID: 35352558
An analytical solution to the kinetics of breakable filament assembly.
Knowles TP, Waudby CA, Devlin GL, Cohen SI, Aguzzi A, Vendruscolo M, Terentjev EM, Welland ME, Dobson CM. Knowles TP, et al. Among authors: aguzzi a. Science. 2009 Dec 11;326(5959):1533-7. doi: 10.1126/science.1178250. Science. 2009. PMID: 20007899
Absolute Quantification of Amyloid Propagons by Digital Microfluidics.
Pfammatter M, Andreasen M, Meisl G, Taylor CG, Adamcik J, Bolisetty S, Sánchez-Ferrer A, Klenerman D, Dobson CM, Mezzenga R, Knowles TPJ, Aguzzi A, Hornemann S. Pfammatter M, et al. Among authors: aguzzi a. Anal Chem. 2017 Nov 21;89(22):12306-12313. doi: 10.1021/acs.analchem.7b03279. Epub 2017 Nov 1. Anal Chem. 2017. PMID: 28972786 Free PMC article.
Scaling behaviour and rate-determining steps in filamentous self-assembly.
Meisl G, Rajah L, Cohen SAI, Pfammatter M, Šarić A, Hellstrand E, Buell AK, Aguzzi A, Linse S, Vendruscolo M, Dobson CM, Knowles TPJ. Meisl G, et al. Among authors: aguzzi a. Chem Sci. 2017 Oct 1;8(10):7087-7097. doi: 10.1039/c7sc01965c. Epub 2017 Aug 31. Chem Sci. 2017. PMID: 29147538 Free PMC article.
Protective anti-prion antibodies in human immunoglobulin repertoires.
Senatore A, Frontzek K, Emmenegger M, Chincisan A, Losa M, Reimann R, Horny G, Guo J, Fels S, Sorce S, Zhu C, George N, Ewert S, Pietzonka T, Hornemann S, Aguzzi A. Senatore A, et al. Among authors: aguzzi a. EMBO Mol Med. 2020 Sep 7;12(9):e12739. doi: 10.15252/emmm.202012739. Epub 2020 Aug 10. EMBO Mol Med. 2020. PMID: 32776637 Free PMC article.
Systemic and mucosal antibody responses specific to SARS-CoV-2 during mild versus severe COVID-19.
Cervia C, Nilsson J, Zurbuchen Y, Valaperti A, Schreiner J, Wolfensberger A, Raeber ME, Adamo S, Weigang S, Emmenegger M, Hasler S, Bosshard PP, De Cecco E, Bächli E, Rudiger A, Stüssi-Helbling M, Huber LC, Zinkernagel AS, Schaer DJ, Aguzzi A, Kochs G, Held U, Probst-Müller E, Rampini SK, Boyman O. Cervia C, et al. Among authors: aguzzi a. J Allergy Clin Immunol. 2021 Feb;147(2):545-557.e9. doi: 10.1016/j.jaci.2020.10.040. Epub 2020 Nov 20. J Allergy Clin Immunol. 2021. PMID: 33221383 Free PMC article.
Scaling analysis reveals the mechanism and rates of prion replication in vivo.
Meisl G, Kurt T, Condado-Morales I, Bett C, Sorce S, Nuvolone M, Michaels TCT, Heinzer D, Avar M, Cohen SIA, Hornemann S, Aguzzi A, Dobson CM, Sigurdson CJ, Knowles TPJ. Meisl G, et al. Among authors: aguzzi a. Nat Struct Mol Biol. 2021 Apr;28(4):365-372. doi: 10.1038/s41594-021-00565-x. Epub 2021 Mar 25. Nat Struct Mol Biol. 2021. PMID: 33767451 Free PMC article.
Antibody Affinity Governs the Inhibition of SARS-CoV-2 Spike/ACE2 Binding in Patient Serum.
Fiedler S, Piziorska MA, Denninger V, Morgunov AS, Ilsley A, Malik AY, Schneider MM, Devenish SRA, Meisl G, Kosmoliaptsis V, Aguzzi A, Fiegler H, Knowles TPJ. Fiedler S, et al. Among authors: aguzzi a. ACS Infect Dis. 2021 Aug 13;7(8):2362-2369. doi: 10.1021/acsinfecdis.1c00047. Epub 2021 Apr 20. ACS Infect Dis. 2021. PMID: 33876632
661 results