El Ghaleb Y - Search Results

1

Calcium current modulation by the γ1 subunit depends on alternative splicing of CaV1.1.

El Ghaleb Y, Ortner NJ, Posch W, Fernández-Quintero ML, Tuinte WE, Monteleone S, Draheim HJ, Liedl KR, Wilflingseder D, Striessnig J, Tuluc P, Flucher BE, Campiglio M. El Ghaleb Y, et al. J Gen Physiol. 2022 Sep 5;154(9):e202113028. doi: 10.1085/jgp.202113028. Epub 2022 Mar 29. J Gen Physiol. 2022. PMID: 35349630 Free PMC article.

2

Correcting the R165K substitution in the first voltage-sensor of Ca_V1.1 right-shifts the voltage-dependence of skeletal muscle calcium channel activation.

El Ghaleb Y, Campiglio M, Flucher BE. El Ghaleb Y, et al. Channels (Austin). 2019 Dec;13(1):62-71. doi: 10.1080/19336950.2019.1568825. Channels (Austin). 2019. PMID: 30638110 Free PMC article.

3

Structural determinants of voltage-gating properties in calcium channels.

Fernández-Quintero ML, El Ghaleb Y, Tuluc P, Campiglio M, Liedl KR, Flucher BE. Fernández-Quintero ML, et al. Among authors: el ghaleb y. Elife. 2021 Mar 30;10:e64087. doi: 10.7554/eLife.64087. Elife. 2021. PMID: 33783354 Free PMC article.

4

Ion-pair interactions between voltage-sensing domain IV and pore domain I regulate Ca_V1.1 gating.

El Ghaleb Y, Fernández-Quintero ML, Monteleone S, Tuluc P, Campiglio M, Liedl KR, Flucher BE. El Ghaleb Y, et al. Biophys J. 2021 Oct 19;120(20):4429-4441. doi: 10.1016/j.bpj.2021.09.004. Epub 2021 Sep 8. Biophys J. 2021. PMID: 34506774 Free PMC article.

5

CACNA1I gain-of-function mutations differentially affect channel gating and cause neurodevelopmental disorders.

El Ghaleb Y, Schneeberger PE, Fernández-Quintero ML, Geisler SM, Pelizzari S, Polstra AM, van Hagen JM, Denecke J, Campiglio M, Liedl KR, Stevens CA, Person RE, Rentas S, Marsh ED, Conlin LK, Tuluc P, Kutsche K, Flucher BE. El Ghaleb Y, et al. Brain. 2021 Aug 17;144(7):2092-2106. doi: 10.1093/brain/awab101. Brain. 2021. PMID: 33704440 Free PMC article.

6

Ca_V1.1 voltage-sensing domain III exclusively controls skeletal muscle excitation-contraction coupling.

Pelizzari S, Heiss MC, Fernández-Quintero ML, El Ghaleb Y, Liedl KR, Tuluc P, Campiglio M, Flucher BE. Pelizzari S, et al. Among authors: el ghaleb y. Nat Commun. 2024 Aug 28;15(1):7440. doi: 10.1038/s41467-024-51809-5. Nat Commun. 2024. PMID: 39198449 Free PMC article.

7

Ca_V3.3 Channelopathies.

El Ghaleb Y, Flucher BE. El Ghaleb Y, et al. Handb Exp Pharmacol. 2023;279:263-288. doi: 10.1007/164_2022_631. Handb Exp Pharmacol. 2023. PMID: 36592228

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