Li X - Search Results

1

Novel inhibitors of AChE and Aβ aggregation with neuroprotective properties as lead compounds for the treatment of Alzheimer's disease.

Liu Y, Uras G, Onuwaje I, Li W, Yao H, Xu S, Li X, Li X, Phillips J, Allen S, Gong Q, Zhang H, Zhu Z, Liu J, Xu J. Liu Y, et al. Among authors: li w, li x. Eur J Med Chem. 2022 May 5;235:114305. doi: 10.1016/j.ejmech.2022.114305. Epub 2022 Mar 18. Eur J Med Chem. 2022. PMID: 35339839

2

Design, synthesis, biological evaluation, and docking study of 4-isochromanone hybrids bearing N-benzyl pyridinium moiety as dual binding site acetylcholinesterase inhibitors (part II).

Wang J, Wang C, Wu Z, Li X, Xu S, Liu J, Lan Q, Zhu Z, Xu J. Wang J, et al. Among authors: li x. Chem Biol Drug Des. 2018 Mar;91(3):756-762. doi: 10.1111/cbdd.13136. Epub 2017 Dec 1. Chem Biol Drug Des. 2018. PMID: 29112799

3

Design, synthesis and biological evaluation of isochroman-4-one hybrids bearing piperazine moiety as antihypertensive agent candidates.

Xie S, Li X, Yu H, Zhang P, Wang J, Wang C, Xu S, Wu Z, Liu J, Zhu Z, Xu J. Xie S, et al. Among authors: li x. Bioorg Med Chem. 2019 Jul 1;27(13):2764-2770. doi: 10.1016/j.bmc.2019.05.004. Epub 2019 May 6. Bioorg Med Chem. 2019. PMID: 31078380

4

Design, synthesis and anticancer properties of isocombretapyridines as potent colchicine binding site inhibitors.

Shuai W, Li X, Li W, Xu F, Lu L, Yao H, Yang L, Zhu H, Xu S, Zhu Z, Xu J. Shuai W, et al. Among authors: li w, li x. Eur J Med Chem. 2020 Jul 1;197:112308. doi: 10.1016/j.ejmech.2020.112308. Epub 2020 Apr 19. Eur J Med Chem. 2020. PMID: 32339853

5

Corrigendum to "Design, synthesis and anticancer properties of isocombretapyridines as potent colchicine binding site inhibitors" [Eur. J. Med. Chem. 197 (2020) 112308].

Shuai W, Li X, Li W, Xu F, Lu L, Yao H, Yang L, Zhu H, Xu S, Zhu Z, Xu J. Shuai W, et al. Among authors: li w, li x. Eur J Med Chem. 2020 Aug 15;200:112464. doi: 10.1016/j.ejmech.2020.112464. Epub 2020 Jun 6. Eur J Med Chem. 2020. PMID: 32512484 No abstract available.

6

Development of Alectinib-Based PROTACs as Novel Potent Degraders of Anaplastic Lymphoma Kinase (ALK).

Xie S, Sun Y, Liu Y, Li X, Li X, Zhong W, Zhan F, Zhu J, Yao H, Yang DH, Chen ZS, Xu J, Xu S. Xie S, et al. Among authors: li x. J Med Chem. 2021 Jul 8;64(13):9120-9140. doi: 10.1021/acs.jmedchem.1c00270. Epub 2021 Jun 28. J Med Chem. 2021. PMID: 34176264

7

Design, synthesis and biological evaluation of hydrogen sulfide-releasing isochroman-4-one derivatives as new antihypertensive agent candidates.

Wu H, Li X, He C, Liu Y, Wang C, Yang X, Ma F, Liu J, Xu J. Wu H, et al. Among authors: li x. Bioorg Med Chem. 2022 Jun 15;64:116776. doi: 10.1016/j.bmc.2022.116776. Epub 2022 Apr 25. Bioorg Med Chem. 2022. PMID: 35483137

8

Novel and Potent Acetylcholinesterase Inhibitors for the Treatment of Alzheimer's Disease from Natural (±)-7,8-Dihydroxy-3-methyl-isochroman-4-one.

Li X, Jia Y, Li J, Zhang P, Li T, Lu L, Yao H, Liu J, Zhu Z, Xu J. Li X, et al. Among authors: li t, li j. Molecules. 2022 May 11;27(10):3090. doi: 10.3390/molecules27103090. Molecules. 2022. PMID: 35630563 Free PMC article.

9

Discovery of novel hybrids containing clioquinol-1-benzyl-1,2,3,6-tetrahydropyridine as multi-target-directed ligands (MTDLs) against Alzheimer's disease.

Li X, Li T, Zhang P, Li X, Lu L, Sun Y, Zhang B, Allen S, White L, Phillips J, Zhu Z, Yao H, Xu J. Li X, et al. Among authors: li t. Eur J Med Chem. 2022 Dec 15;244:114841. doi: 10.1016/j.ejmech.2022.114841. Epub 2022 Oct 12. Eur J Med Chem. 2022. PMID: 36257284

10

Design, Synthesis, and Biological Evaluation of Novel Chromanone Derivatives as Multifunctional Agents for the Treatment of Alzheimer's Disease.

Li X, Li T, Zhan F, Cheng F, Lu L, Zhang B, Li J, Hu Z, Zhou S, Jia Y, Allen S, White L, Phillips J, Zhu Z, Xu J, Yao H. Li X, et al. Among authors: li t, li j. ACS Chem Neurosci. 2022 Dec 7;13(23):3488-3501. doi: 10.1021/acschemneuro.2c00520. Epub 2022 Nov 16. ACS Chem Neurosci. 2022. PMID: 36383455

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