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162 results

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Pre- and post-treatment blood-based genomic landscape of patients with ROS1 or NTRK fusion-positive solid tumours treated with entrectinib.
Dziadziuszko R, Hung T, Wang K, Choeurng V, Drilon A, Doebele RC, Barlesi F, Wu C, Dennis L, Skoletsky J, Woodhouse R, Li M, Chang CW, Simmons B, Riehl T, Wilson TR. Dziadziuszko R, et al. Among authors: doebele rc. Mol Oncol. 2022 May;16(10):2000-2014. doi: 10.1002/1878-0261.13214. Epub 2022 Apr 22. Mol Oncol. 2022. PMID: 35338679 Free PMC article.
Identifying and targeting ROS1 gene fusions in non-small cell lung cancer.
Davies KD, Le AT, Theodoro MF, Skokan MC, Aisner DL, Berge EM, Terracciano LM, Cappuzzo F, Incarbone M, Roncalli M, Alloisio M, Santoro A, Camidge DR, Varella-Garcia M, Doebele RC. Davies KD, et al. Among authors: doebele rc. Clin Cancer Res. 2012 Sep 1;18(17):4570-9. doi: 10.1158/1078-0432.CCR-12-0550. Epub 2012 Aug 23. Clin Cancer Res. 2012. PMID: 22919003 Free PMC article.
Molecular pathways: ROS1 fusion proteins in cancer.
Davies KD, Doebele RC. Davies KD, et al. Among authors: doebele rc. Clin Cancer Res. 2013 Aug 1;19(15):4040-5. doi: 10.1158/1078-0432.CCR-12-2851. Epub 2013 May 29. Clin Cancer Res. 2013. PMID: 23719267 Free PMC article. Review.
ROS1 and ALK fusions in colorectal cancer, with evidence of intratumoral heterogeneity for molecular drivers.
Aisner DL, Nguyen TT, Paskulin DD, Le AT, Haney J, Schulte N, Chionh F, Hardingham J, Mariadason J, Tebbutt N, Doebele RC, Weickhardt AJ, Varella-Garcia M. Aisner DL, et al. Among authors: doebele rc. Mol Cancer Res. 2014 Jan;12(1):111-8. doi: 10.1158/1541-7786.MCR-13-0479-T. Epub 2013 Dec 2. Mol Cancer Res. 2014. PMID: 24296758 Free PMC article. Clinical Trial.
The minority report: targeting the rare oncogenes in NSCLC.
McCoach CE, Doebele RC. McCoach CE, et al. Among authors: doebele rc. Curr Treat Options Oncol. 2014 Dec;15(4):644-57. doi: 10.1007/s11864-014-0310-8. Curr Treat Options Oncol. 2014. PMID: 25228144 Free PMC article. Review.
Activation of RAS family members confers resistance to ROS1 targeting drugs.
Cargnelutti M, Corso S, Pergolizzi M, Mévellec L, Aisner DL, Dziadziuszko R, Varella-Garcia M, Comoglio PM, Doebele RC, Vialard J, Giordano S. Cargnelutti M, et al. Among authors: doebele rc. Oncotarget. 2015 Mar 10;6(7):5182-94. doi: 10.18632/oncotarget.3311. Oncotarget. 2015. PMID: 25691052 Free PMC article.
Rociletinib in EGFR-mutated non-small-cell lung cancer.
Sequist LV, Soria JC, Goldman JW, Wakelee HA, Gadgeel SM, Varga A, Papadimitrakopoulou V, Solomon BJ, Oxnard GR, Dziadziuszko R, Aisner DL, Doebele RC, Galasso C, Garon EB, Heist RS, Logan J, Neal JW, Mendenhall MA, Nichols S, Piotrowska Z, Wozniak AJ, Raponi M, Karlovich CA, Jaw-Tsai S, Isaacson J, Despain D, Matheny SL, Rolfe L, Allen AR, Camidge DR. Sequist LV, et al. Among authors: doebele rc. N Engl J Med. 2015 Apr 30;372(18):1700-9. doi: 10.1056/NEJMoa1413654. N Engl J Med. 2015. PMID: 25923550 Free article. Clinical Trial.
162 results