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In vitro anti-inflammatory effects of AZD8999, a novel bifunctional muscarinic acetylcholine receptor antagonist /β2-adrenoceptor agonist (MABA) compound in neutrophils from COPD patients.
Milara J, Contreras S, de Diego A, Calbet M, Aparici M, Morcillo E, Miralpeix M, Cortijo J. Milara J, et al. Among authors: miralpeix m. PLoS One. 2019 Jan 4;14(1):e0210188. doi: 10.1371/journal.pone.0210188. eCollection 2019. PLoS One. 2019. PMID: 30608978 Free PMC article.
Novel Inhaled Pan-JAK Inhibitor, LAS194046, Reduces Allergen-Induced Airway Inflammation, Late Asthmatic Response, and pSTAT Activation in Brown Norway Rats.
Calbet M, Ramis I, Calama E, Carreño C, Paris S, Maldonado M, Orellana A, Calaf E, Pauta M, De Alba J, Bach J, Miralpeix M. Calbet M, et al. Among authors: miralpeix m. J Pharmacol Exp Ther. 2019 Aug;370(2):137-147. doi: 10.1124/jpet.119.256263. Epub 2019 May 13. J Pharmacol Exp Ther. 2019. PMID: 31085698
Aclidinium inhibits human lung fibroblast to myofibroblast transition.
Milara J, Serrano A, Peiró T, Gavaldà A, Miralpeix M, Morcillo EJ, Cortijo J. Milara J, et al. Among authors: miralpeix m. Thorax. 2012 Mar;67(3):229-37. doi: 10.1136/thoraxjnl-2011-200376. Epub 2011 Sep 28. Thorax. 2012. PMID: 21957094 Free PMC article.
Identification of 2-Imidazopyridine and 2-Aminopyridone Purinones as Potent Pan-Janus Kinase (JAK) Inhibitors for the Inhaled Treatment of Respiratory Diseases.
Bach J, Eastwood P, González J, Gómez E, Alonso JA, Fonquerna S, Lozoya E, Orellana A, Maldonado M, Calaf E, Albertí J, Pérez J, Andrés A, Prats N, Carreño C, Calama E, De Alba J, Calbet M, Miralpeix M, Ramis I. Bach J, et al. Among authors: miralpeix m. J Med Chem. 2019 Oct 24;62(20):9045-9060. doi: 10.1021/acs.jmedchem.9b00533. Epub 2019 Oct 14. J Med Chem. 2019. PMID: 31609613
88 results