Qin X - Search Results

1

ZDQ-0620, a Novel Phosphatidylinositol 3-Kinase Inhibitor, Inhibits Colorectal Carcinoma Cell Proliferation and Suppresses Angiogenesis by Attenuating PI3K/AKT/mTOR Pathway.

Qin X, Liu M, Xu C, Xing B, Xu X, Wu Y, Ding H, Zhao Q. Qin X, et al. Front Oncol. 2022 Mar 2;12:848952. doi: 10.3389/fonc.2022.848952. eCollection 2022. Front Oncol. 2022. PMID: 35311154 Free PMC article.

2

CK-3, A Novel Methsulfonyl Pyridine Derivative, Suppresses Hepatocellular Carcinoma Proliferation and Invasion by Blocking the PI3K/AKT/mTOR and MAPK/ERK Pathways.

Wu Q, Liu TY, Hu BC, Li X, Wu YT, Sun XT, Jiang XW, Wang S, Qin XC, Ding HW, Zhao QC. Wu Q, et al. Among authors: qin xc. Front Oncol. 2021 Jul 28;11:717626. doi: 10.3389/fonc.2021.717626. eCollection 2021. Front Oncol. 2021. PMID: 34395292 Free PMC article.

3

DZW-310, a novel phosphoinositide 3-kinase inhibitor, attenuates the angiogenesis and growth of hepatocellular carcinoma cells via PI3K/AKT/mTOR axis.

Wu Y, Xu X, Liu M, Qin X, Wu Q, Ding H, Zhao Q. Wu Y, et al. Among authors: qin x. Biochem Pharmacol. 2022 Jul;201:115093. doi: 10.1016/j.bcp.2022.115093. Epub 2022 May 14. Biochem Pharmacol. 2022. PMID: 35580648

4

DHW-221, a Dual PI3K/mTOR Inhibitor, Overcomes Multidrug Resistance by Targeting P-Glycoprotein (P-gp/ABCB1) and Akt-Mediated FOXO3a Nuclear Translocation in Non-small Cell Lung Cancer.

Liu M, Xu C, Qin X, Liu W, Li D, Jia H, Gao X, Wu Y, Wu Q, Xu X, Xing B, Jiang X, Lu H, Zhang Y, Ding H, Zhao Q. Liu M, et al. Among authors: qin x. Front Oncol. 2022 May 13;12:873649. doi: 10.3389/fonc.2022.873649. eCollection 2022. Front Oncol. 2022. PMID: 35646704 Free PMC article.

5

Design, synthesis, and biological evaluation of some novel 4-aminoquinazolines as Pan-PI3K inhibitors.

Ding HW, Wang S, Qin XC, Wang J, Song HR, Zhao QC, Song SJ. Ding HW, et al. Bioorg Med Chem. 2019 Jul 1;27(13):2729-2740. doi: 10.1016/j.bmc.2019.04.024. Epub 2019 Apr 17. Bioorg Med Chem. 2019. PMID: 31097403

6

Design, synthesis and evaluation of some 1,6-disubstituted-1H-benzo[d]imidazoles derivatives targeted PI3K as anticancer agents.

Ding HW, Yu L, Bai MX, Qin XC, Song MT, Zhao QC. Ding HW, et al. Bioorg Chem. 2019 Dec;93:103283. doi: 10.1016/j.bioorg.2019.103283. Epub 2019 Sep 14. Bioorg Chem. 2019. PMID: 31585260

7

Novel ADAM-17 inhibitor ZLDI-8 inhibits the metastasis of hepatocellular carcinoma by reversing epithelial-mesenchymal transition in vitro and in vivo.

Lu HY, Chu HX, Tan YX, Qin XC, Liu MY, Li JD, Ren TS, Zhang YS, Zhao QC. Lu HY, et al. Life Sci. 2020 Mar 1;244:117343. doi: 10.1016/j.lfs.2020.117343. Epub 2020 Jan 21. Life Sci. 2020. PMID: 31978449

8

Alpinia oxyphylla oil induces apoptosis of hepatocellular carcinoma cells via PI3K/Akt pathway in vitro and in vivo.

Hui F, Qin X, Zhang Q, Li R, Liu M, Ren T, Zhao M, Zhao Q. Hui F, et al. Among authors: qin x. Biomed Pharmacother. 2019 Jan;109:2365-2374. doi: 10.1016/j.biopha.2018.11.124. Epub 2018 Nov 30. Biomed Pharmacother. 2019. PMID: 30551496 Free article.

9

A novel 4-aminoquinazoline derivative, DHW-208, suppresses the growth of human breast cancer cells by targeting the PI3K/AKT/mTOR pathway.

Wang S, Zhang Y, Ren T, Wu Q, Lu H, Qin X, Liu Y, Ding H, Zhao Q. Wang S, et al. Among authors: qin x. Cell Death Dis. 2020 Jun 30;11(6):491. doi: 10.1038/s41419-020-2690-y. Cell Death Dis. 2020. PMID: 32606352 Free PMC article.

10

PI3K/AKT/mTOR pathway-related long non-coding RNAs: roles and mechanisms in hepatocellular carcinoma.

Wu Y, Zhang Y, Qin X, Geng H, Zuo D, Zhao Q. Wu Y, et al. Among authors: qin x. Pharmacol Res. 2020 Oct;160:105195. doi: 10.1016/j.phrs.2020.105195. Epub 2020 Sep 8. Pharmacol Res. 2020. PMID: 32916254 Review.

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