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The Pathogenic Sphingolipid Psychosine is Secreted in Extracellular Vesicles in the Brain of a Mouse Model of Krabbe Disease.
Reiter CR, Rebiai R, Kwak A, Marshall J, Wozniak D, Scesa G, Nguyen D, Rue E, Pathmasiri C, Pijewski R, van Breemen R, Cologna S, Crocker SJ, Givogri MI, Bongarzone ER. Reiter CR, et al. Among authors: givogri mi. ASN Neuro. 2022 Jan-Dec;14:17590914221087817. doi: 10.1177/17590914221087817. ASN Neuro. 2022. PMID: 35300522 Free PMC article.
Axonopathy is a compounding factor in the pathogenesis of Krabbe disease.
Castelvetri LC, Givogri MI, Zhu H, Smith B, Lopez-Rosas A, Qiu X, van Breemen R, Bongarzone ER. Castelvetri LC, et al. Among authors: givogri mi. Acta Neuropathol. 2011 Jul;122(1):35-48. doi: 10.1007/s00401-011-0814-2. Epub 2011 Mar 4. Acta Neuropathol. 2011. PMID: 21373782 Free PMC article.
Neuronal inclusions of α-synuclein contribute to the pathogenesis of Krabbe disease.
Smith BR, Santos MB, Marshall MS, Cantuti-Castelvetri L, Lopez-Rosas A, Li G, van Breemen R, Claycomb KI, Gallea JI, Celej MS, Crocker SJ, Givogri MI, Bongarzone ER. Smith BR, et al. Among authors: givogri mi. J Pathol. 2014 Apr;232(5):509-21. doi: 10.1002/path.4328. Epub 2014 Feb 20. J Pathol. 2014. PMID: 24415155 Free PMC article.
Long-Term Improvement of Neurological Signs and Metabolic Dysfunction in a Mouse Model of Krabbe's Disease after Global Gene Therapy.
Marshall MS, Issa Y, Jakubauskas B, Stoskute M, Elackattu V, Marshall JN, Bogue W, Nguyen D, Hauck Z, Rue E, Karumuthil-Melethil S, Zaric V, Bosland M, van Breemen RB, Givogri MI, Gray SJ, Crocker SJ, Bongarzone ER. Marshall MS, et al. Among authors: givogri mi. Mol Ther. 2018 Mar 7;26(3):874-889. doi: 10.1016/j.ymthe.2018.01.009. Epub 2018 Jan 17. Mol Ther. 2018. PMID: 29433937 Free PMC article.
Waning efficacy in a long-term AAV-mediated gene therapy study in the murine model of Krabbe disease.
Heller GJ, Marshall MS, Issa Y, Marshall JN, Nguyen D, Rue E, Pathmasiri KC, Domowicz MS, van Breemen RB, Tai LM, Cologna SM, Crocker SJ, Givogri MI, Sands MS, Bongarzone ER. Heller GJ, et al. Among authors: givogri mi. Mol Ther. 2021 May 5;29(5):1883-1902. doi: 10.1016/j.ymthe.2021.01.026. Epub 2021 Jan 26. Mol Ther. 2021. PMID: 33508430 Free PMC article.
48 results