Nijhuis A - Search Results

1

Indisulam targets RNA splicing and metabolism to serve as a therapeutic strategy for high-risk neuroblastoma.

Nijhuis A, Sikka A, Yogev O, Herendi L, Balcells C, Ma Y, Poon E, Eckold C, Valbuena GN, Xu Y, Liu Y, da Costa BM, Gruet M, Wickremesinghe C, Benito A, Kramer H, Montoya A, Carling D, Want EJ, Jamin Y, Chesler L, Keun HC. Nijhuis A, et al. Nat Commun. 2022 Mar 16;13(1):1380. doi: 10.1038/s41467-022-28907-3. Nat Commun. 2022. PMID: 35296644 Free PMC article.

2

Lactic acidosis induces resistance to the pan-Akt inhibitor uprosertib in colon cancer cells.

Barnes EME, Xu Y, Benito A, Herendi L, Siskos AP, Aboagye EO, Nijhuis A, Keun HC. Barnes EME, et al. Among authors: nijhuis a. Br J Cancer. 2020 Apr;122(9):1298-1308. doi: 10.1038/s41416-020-0777-y. Epub 2020 Mar 10. Br J Cancer. 2020. PMID: 32152504 Free PMC article.

3

RNA-binding motif protein 39 (RBM39): An emerging cancer target.

Xu Y, Nijhuis A, Keun HC. Xu Y, et al. Among authors: nijhuis a. Br J Pharmacol. 2022 Jun;179(12):2795-2812. doi: 10.1111/bph.15331. Epub 2021 Jan 3. Br J Pharmacol. 2022. PMID: 33238031 Free article. Review.

4

Pharmacological depletion of RNA splicing factor RBM39 by indisulam synergizes with PARP inhibitors in high-grade serous ovarian carcinoma.

Xu Y, Spear S, Ma Y, Lorentzen MP, Gruet M, McKinney F, Xu Y, Wickremesinghe C, Shepherd MR, McNeish I, Keun HC, Nijhuis A. Xu Y, et al. Among authors: nijhuis a. Cell Rep. 2023 Oct 31;42(10):113307. doi: 10.1016/j.celrep.2023.113307. Epub 2023 Oct 19. Cell Rep. 2023. PMID: 37858464 Free article.

5

RBM39: A druggable metabolic sensor linking RNA splicing, transcriptional regulation, and metabolic reprogramming in cancer.

Keun HC, Nijhuis A. Keun HC, et al. Among authors: nijhuis a. Mol Cell. 2023 Dec 7;83(23):4202-4204. doi: 10.1016/j.molcel.2023.11.012. Mol Cell. 2023. PMID: 38065060 Free article.

6

Epigenetic and Metabolic Reprogramming of Fibroblasts in Crohn's Disease Strictures Reveals Histone Deacetylases as Therapeutic Targets.

Lewis A, Humphreys DT, Pan-Castillo B, Berti G, Felice C, Gordon H, Gadhok R, Nijhuis A, Mehta S S, Eleid L, Iqbal S, Armuzzi A, Minicozzi A, Giannoulatou E, ChinAleong J, Feakins R, Sagi-Kiss V, Barisic D, Koufaki MI, Bundy JG, Lindsay JO, Silver A. Lewis A, et al. Among authors: nijhuis a. J Crohns Colitis. 2024 Jun 3;18(6):895-907. doi: 10.1093/ecco-jcc/jjad209. J Crohns Colitis. 2024. PMID: 38069679 Free PMC article.

7

Remodelling of microRNAs in colorectal cancer by hypoxia alters metabolism profiles and 5-fluorouracil resistance.

Nijhuis A, Thompson H, Adam J, Parker A, Gammon L, Lewis A, Bundy JG, Soga T, Jalaly A, Propper D, Jeffery R, Suraweera N, McDonald S, Thaha MA, Feakins R, Lowe R, Bishop CL, Silver A. Nijhuis A, et al. Hum Mol Genet. 2017 Apr 15;26(8):1552-1564. doi: 10.1093/hmg/ddx059. Hum Mol Genet. 2017. PMID: 28207045 Free PMC article.

8

Role of Reactive Oxygen Species in the Abrogation of Oxaliplatin Activity by Cetuximab in Colorectal Cancer.

Santoro V, Jia R, Thompson H, Nijhuis A, Jeffery R, Kiakos K, Silver AR, Hartley JA, Hochhauser D. Santoro V, et al. Among authors: nijhuis a. J Natl Cancer Inst. 2015 Dec 30;108(6):djv394. doi: 10.1093/jnci/djv394. Print 2016 Jun. J Natl Cancer Inst. 2015. PMID: 26719345 Free PMC article.

9

Small-molecule Wnt inhibitors are a potential novel therapy for intestinal fibrosis in Crohns disease.

Lewis A, Sánchez S, Berti G, Pan-Castillo B, Nijhuis A, Mehta S, Eleid L, Gordon H, Gadhok R, Kimberley C, Minicozzi A, Chin-Aleong J, Feakins R, Kypta R, Lindsay JO, Silver A. Lewis A, et al. Among authors: nijhuis a. Clin Sci (Lond). 2022 Oct 14;136(19):1405-1423. doi: 10.1042/CS20210889. Clin Sci (Lond). 2022. PMID: 36156078 Free PMC article.

10

DUOX2 and DUOXA2 form the predominant enzyme system capable of producing the reactive oxygen species H2O2 in active ulcerative colitis and are modulated by 5-aminosalicylic acid.

MacFie TS, Poulsom R, Parker A, Warnes G, Boitsova T, Nijhuis A, Suraweera N, Poehlmann A, Szary J, Feakins R, Jeffery R, Harper RW, Jubb AM, Lindsay JO, Silver A. MacFie TS, et al. Among authors: nijhuis a. Inflamm Bowel Dis. 2014 Mar;20(3):514-24. doi: 10.1097/01.MIB.0000442012.45038.0e. Inflamm Bowel Dis. 2014. PMID: 24492313

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

46 results

Search Page

Filters