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Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause severe disease.
Zhou P, Song G, He WT, Beutler N, Tse LV, Martinez DR, Schäfer A, Anzanello F, Yong P, Peng L, Dueker K, Musharrafieh R, Callaghan S, Capozzola T, Yuan M, Liu H, Limbo O, Parren M, Garcia E, Rawlings SA, Smith DM, Nemazee D, Jardine JG, Wilson IA, Safonova Y, Rogers TF, Baric RS, Gralinski LE, Burton DR, Andrabi R. Zhou P, et al. Among authors: burton dr. bioRxiv [Preprint]. 2022 Mar 7:2022.03.04.479488. doi: 10.1101/2022.03.04.479488. bioRxiv. 2022. Update in: Immunity. 2023 Mar 14;56(3):669-686.e7. doi: 10.1016/j.immuni.2023.02.005 PMID: 35291291 Free PMC article. Updated. Preprint.
Covalent display of oligosaccharide arrays in microtiter plates.
Bryan MC, Fazio F, Lee HK, Huang CY, Chang A, Best MD, Calarese DA, Blixt O, Paulson JC, Burton D, Wilson IA, Wong CH. Bryan MC, et al. J Am Chem Soc. 2004 Jul 21;126(28):8640-1. doi: 10.1021/ja048433f. J Am Chem Soc. 2004. PMID: 15250702
Site-specific steric control of SARS-CoV-2 spike glycosylation.
Allen JD, Chawla H, Samsudin F, Zuzic L, Shivgan AT, Watanabe Y, He WT, Callaghan S, Song G, Yong P, Brouwer PJM, Song Y, Cai Y, Duyvesteyn HME, Malinauskas T, Kint J, Pino P, Wurm MJ, Frank M, Chen B, Stuart DI, Sanders RW, Andrabi R, Burton DR, Li S, Bond PJ, Crispin M. Allen JD, et al. Among authors: burton dr. bioRxiv [Preprint]. 2021 Mar 9:2021.03.08.433764. doi: 10.1101/2021.03.08.433764. bioRxiv. 2021. Update in: Biochemistry. 2021 Jul 13;60(27):2153-2169. doi: 10.1021/acs.biochem.1c00279 PMID: 33758835 Free PMC article. Updated. Preprint.
A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection.
Zhou P, Yuan M, Song G, Beutler N, Shaabani N, Huang D, He WT, Zhu X, Callaghan S, Yong P, Anzanello F, Peng L, Ricketts J, Parren M, Garcia E, Rawlings SA, Smith DM, Nemazee D, Teijaro JR, Rogers TF, Wilson IA, Burton DR, Andrabi R. Zhou P, et al. Among authors: burton dr. bioRxiv [Preprint]. 2022 Jan 21:2021.03.30.437769. doi: 10.1101/2021.03.30.437769. bioRxiv. 2022. Update in: Sci Transl Med. 2022 Mar 23;14(637):eabi9215. doi: 10.1126/scitranslmed.abi9215 PMID: 33821273 Free PMC article. Updated. Preprint.
Targeted isolation of panels of diverse human protective broadly neutralizing antibodies against SARS-like viruses.
He WT, Musharrafieh R, Song G, Dueker K, Tse LV, Martinez DR, Schäfer A, Callaghan S, Yong P, Beutler N, Torres JL, Volk RM, Zhou P, Yuan M, Liu H, Anzanello F, Capozzola T, Parren M, Garcia E, Rawlings SA, Smith DM, Wilson IA, Safonova Y, Ward AB, Rogers TF, Baric RS, Gralinski LE, Burton DR, Andrabi R. He WT, et al. Among authors: burton dr. bioRxiv [Preprint]. 2022 Feb 8:2021.09.08.459480. doi: 10.1101/2021.09.08.459480. bioRxiv. 2022. Update in: Nat Immunol. 2022 Jun;23(6):960-970. doi: 10.1038/s41590-022-01222-1 PMID: 35169804 Free PMC article. Updated. Preprint.
A broad and potent neutralization epitope in SARS-related coronaviruses.
Yuan M, Zhu X, He WT, Zhou P, Kaku CI, Capozzola T, Zhu CY, Yu X, Liu H, Yu W, Hua Y, Tien H, Peng L, Song G, Cottrell CA, Schief WR, Nemazee D, Walker LM, Andrabi R, Burton DR, Wilson IA. Yuan M, et al. Among authors: burton dr. bioRxiv [Preprint]. 2022 Mar 14:2022.03.13.484037. doi: 10.1101/2022.03.13.484037. bioRxiv. 2022. Update in: Proc Natl Acad Sci U S A. 2022 Jul 19;119(29):e2205784119. doi: 10.1073/pnas.2205784119 PMID: 35313576 Free PMC article. Updated. Preprint.
Targeted protein S-nitrosylation of ACE2 as potential treatment to prevent spread of SARS-CoV-2 infection.
Oh CK, Nakamura T, Beutler N, Zhang X, Piña-Crespo J, Talantova M, Ghatak S, Trudler D, Carnevale LN, McKercher SR, Bakowski MA, Diedrich JK, Roberts AJ, Woods AK, Chi V, Gupta AK, Rosenfeld MA, Kearns FL, Casalino L, Shaabani N, Liu H, Wilson IA, Amaro RE, Burton DR, Yates JR, Becker C, Rogers TF, Chatterjee AK, Lipton SA. Oh CK, et al. Among authors: burton dr. bioRxiv [Preprint]. 2022 Apr 5:2022.04.05.487060. doi: 10.1101/2022.04.05.487060. bioRxiv. 2022. Update in: Nat Chem Biol. 2023 Mar;19(3):275-283. doi: 10.1038/s41589-022-01149-6 PMID: 35411336 Free PMC article. Updated. Preprint.
Evolution of antibody immunity following Omicron BA.1 breakthrough infection.
Kaku CI, Starr TN, Zhou P, Dugan HL, Khalifé P, Song G, Champney ER, Mielcarz DW, Geoghegan JC, Burton DR, Raiees A, Bloom JD, Walker LM. Kaku CI, et al. Among authors: burton dr. bioRxiv [Preprint]. 2022 Sep 22:2022.09.21.508922. doi: 10.1101/2022.09.21.508922. bioRxiv. 2022. Update in: Nat Commun. 2023 May 12;14(1):2751. doi: 10.1038/s41467-023-38345-4 PMID: 36172124 Free PMC article. Updated. Preprint.
A pseudovirus system enables deep mutational scanning of the full SARS-CoV-2 spike.
Dadonaite B, Crawford KHD, Radford CE, Farrell AG, Yu TC, Hannon WW, Zhou P, Andrabi R, Burton DR, Liu L, Ho DD, Neher RA, Bloom JD. Dadonaite B, et al. Among authors: burton dr. bioRxiv [Preprint]. 2022 Oct 13:2022.10.13.512056. doi: 10.1101/2022.10.13.512056. bioRxiv. 2022. Update in: Cell. 2023 Mar 16;186(6):1263-1278.e20. doi: 10.1016/j.cell.2023.02.001 PMID: 36263061 Free PMC article. Updated. Preprint.
669 results