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Siglec-5 is an inhibitory immune checkpoint molecule for human T cells.
Vuchkovska A, Glanville DG, Scurti GM, Nishimura MI, White P, Ulijasz AT, Iwashima M. Vuchkovska A, et al. Among authors: scurti gm. Immunology. 2022 Jun;166(2):238-248. doi: 10.1111/imm.13470. Epub 2022 Apr 1. Immunology. 2022. PMID: 35290663 Free PMC article.
Promoting thiol expression increases the durability of antitumor T-cell functions.
Kesarwani P, Al-Khami AA, Scurti G, Thyagarajan K, Kaur N, Husain S, Fang Q, Naga OS, Simms P, Beeson G, Voelkel-Johnson C, Garrett-Mayer E, Beeson CC, Nishimura MI, Mehrotra S. Kesarwani P, et al. Cancer Res. 2014 Nov 1;74(21):6036-6047. doi: 10.1158/0008-5472.CAN-14-1084. Epub 2014 Aug 27. Cancer Res. 2014. PMID: 25164014 Free PMC article.
TCR gene-modified T cells can efficiently treat established hepatitis C-associated hepatocellular carcinoma tumors.
Spear TT, Callender GG, Roszkowski JJ, Moxley KM, Simms PE, Foley KC, Murray DC, Scurti GM, Li M, Thomas JT, Langerman A, Garrett-Mayer E, Zhang Y, Nishimura MI. Spear TT, et al. Among authors: scurti gm. Cancer Immunol Immunother. 2016 Mar;65(3):293-304. doi: 10.1007/s00262-016-1800-2. Epub 2016 Feb 3. Cancer Immunol Immunother. 2016. PMID: 26842125 Free PMC article.
Hepatitis C virus-cross-reactive TCR gene-modified T cells: a model for immunotherapy against diseases with genomic instability.
Spear TT, Riley TP, Lyons GE, Callender GG, Roszkowski JJ, Wang Y, Simms PE, Scurti GM, Foley KC, Murray DC, Hellman LM, McMahan RH, Iwashima M, Garrett-Mayer E, Rosen HR, Baker BM, Nishimura MI. Spear TT, et al. Among authors: scurti gm. J Leukoc Biol. 2016 Sep;100(3):545-57. doi: 10.1189/jlb.2A1215-561R. Epub 2016 Feb 26. J Leukoc Biol. 2016. PMID: 26921345 Free PMC article.
Enhanced stimulation of human tumor-specific T cells by dendritic cells matured in the presence of interferon-γ and multiple toll-like receptor agonists.
Lövgren T, Sarhan D, Truxová I, Choudhary B, Maas R, Melief J, Nyström M, Edbäck U, Vermeij R, Scurti G, Nishimura M, Masucci G, Karlsson-Parra A, Lundqvist A, Adamson L, Kiessling R. Lövgren T, et al. Cancer Immunol Immunother. 2017 Oct;66(10):1333-1344. doi: 10.1007/s00262-017-2029-4. Epub 2017 Jun 10. Cancer Immunol Immunother. 2017. PMID: 28601925 Free PMC article.
21 results