Yang F - Search Results

1

Design, Synthesis, and Biological Evaluation of Aminoindazole Derivatives as Highly Selective Covalent Inhibitors of Wild-Type and Gatekeeper Mutant FGFR4.

Shao M, Chen X, Yang F, Song X, Zhou Y, Lin Q, Fu Y, Ortega R, Lin X, Tu Z, Patterson AV, Smaill JB, Chen Y, Lu X. Shao M, et al. Among authors: yang f. J Med Chem. 2022 Mar 24;65(6):5113-5133. doi: 10.1021/acs.jmedchem.2c00096. Epub 2022 Mar 10. J Med Chem. 2022. PMID: 35271262

2

Synthesis, biological evaluation, and molecular docking investigation of 3-amidoindoles as potent tubulin polymerization inhibitors.

Chen P, Zhuang YX, Diao PC, Yang F, Wu SY, Lv L, You WW, Zhao PL. Chen P, et al. Among authors: yang f. Eur J Med Chem. 2019 Jan 15;162:525-533. doi: 10.1016/j.ejmech.2018.11.038. Epub 2018 Nov 17. Eur J Med Chem. 2019. PMID: 30472600

3

Synthesis, and biological evaluation of 3,6-diaryl-[1,2,4]triazolo[4,3-a]pyridine analogues as new potent tubulin polymerization inhibitors.

Yang F, Jian XE, Diao PC, Huo XS, You WW, Zhao PL. Yang F, et al. Eur J Med Chem. 2020 Oct 15;204:112625. doi: 10.1016/j.ejmech.2020.112625. Epub 2020 Jul 19. Eur J Med Chem. 2020. PMID: 32717486

4

Development of triazolothiadiazine derivatives as highly potent tubulin polymerization inhibitors: Structure-activity relationship, in vitro and in vivo study.

Ma W, Chen P, Huo X, Ma Y, Li Y, Diao P, Yang F, Zheng S, Hu M, You W, Zhao P. Ma W, et al. Among authors: yang f. Eur J Med Chem. 2020 Dec 15;208:112847. doi: 10.1016/j.ejmech.2020.112847. Epub 2020 Sep 18. Eur J Med Chem. 2020. PMID: 33022479

5

Discovery of highly potent tubulin polymerization inhibitors: Design, synthesis, and structure-activity relationships of novel 2,7-diaryl-[1,2,4]triazolo[1,5-a]pyrimidines.

Huo XS, Jian XE, Ou-Yang J, Chen L, Yang F, Lv DX, You WW, Rao JJ, Zhao PL. Huo XS, et al. Among authors: yang f. Eur J Med Chem. 2021 Aug 5;220:113449. doi: 10.1016/j.ejmech.2021.113449. Epub 2021 Apr 16. Eur J Med Chem. 2021. PMID: 33895499

6

Efficient targeted oncogenic KRAS^G12C degradation via first reversible-covalent PROTAC.

Yang F, Wen Y, Wang C, Zhou Y, Zhou Y, Zhang ZM, Liu T, Lu X. Yang F, et al. Eur J Med Chem. 2022 Feb 15;230:114088. doi: 10.1016/j.ejmech.2021.114088. Epub 2022 Jan 3. Eur J Med Chem. 2022. PMID: 35007863

7

Targeting Gatekeeper Mutations for Kinase Drug Discovery.

Zhou Y, Xiang S, Yang F, Lu X. Zhou Y, et al. Among authors: yang f. J Med Chem. 2022 Dec 8;65(23):15540-15558. doi: 10.1021/acs.jmedchem.2c01361. Epub 2022 Nov 17. J Med Chem. 2022. PMID: 36395392 Review.

8

Dual-Targeted Selenium Nanoparticles for Synergistic Photothermal Therapy and Chemotherapy of Tumors.

Fang X, Li C, Zheng L, Yang F, Chen T. Fang X, et al. Among authors: yang f. Chem Asian J. 2018 Apr 16;13(8):996-1004. doi: 10.1002/asia.201800048. Epub 2018 Mar 13. Chem Asian J. 2018. PMID: 29397011

9

Discovery and optimization of 3,4,5-trimethoxyphenyl substituted triazolylthioacetamides as potent tubulin polymerization inhibitors.

Yang F, He CP, Diao PC, Hong KH, Rao JJ, Zhao PL. Yang F, et al. Bioorg Med Chem Lett. 2019 Jan 1;29(1):22-27. doi: 10.1016/j.bmcl.2018.11.024. Epub 2018 Nov 13. Bioorg Med Chem Lett. 2019. PMID: 30448234

10

Simple Aggregation-Induced Emission-Based Multifunctional Fluorescent Dots for Cancer Therapy In Vitro.

Lin X, Zhao J, Huang W, Liu H, Feng P, Yang F, Chen T. Lin X, et al. Among authors: yang f. Chem Asian J. 2019 Dec 2;14(23):4160-4163. doi: 10.1002/asia.201901315. Epub 2019 Nov 28. Chem Asian J. 2019. PMID: 31657112

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