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The RNA helicase DHX16 recognizes specific viral RNA to trigger RIG-I-dependent innate antiviral immunity.
Hage A, Bharaj P, van Tol S, Giraldo MI, Gonzalez-Orozco M, Valerdi KM, Warren AN, Aguilera-Aguirre L, Xie X, Widen SG, Moulton HM, Lee B, Johnson JR, Krogan NJ, García-Sastre A, Shi PY, Freiberg AN, Rajsbaum R. Hage A, et al. Among authors: rajsbaum r. Cell Rep. 2022 Mar 8;38(10):110434. doi: 10.1016/j.celrep.2022.110434. Cell Rep. 2022. PMID: 35263596 Free PMC article.
HERC6 is the main E3 ligase for global ISG15 conjugation in mouse cells.
Oudshoorn D, van Boheemen S, Sánchez-Aparicio MT, Rajsbaum R, García-Sastre A, Versteeg GA. Oudshoorn D, et al. Among authors: rajsbaum r. PLoS One. 2012;7(1):e29870. doi: 10.1371/journal.pone.0029870. Epub 2012 Jan 17. PLoS One. 2012. PMID: 22272257 Free PMC article.
Dengue virus co-opts UBR4 to degrade STAT2 and antagonize type I interferon signaling.
Morrison J, Laurent-Rolle M, Maestre AM, Rajsbaum R, Pisanelli G, Simon V, Mulder LC, Fernandez-Sesma A, García-Sastre A. Morrison J, et al. Among authors: rajsbaum r. PLoS Pathog. 2013 Mar;9(3):e1003265. doi: 10.1371/journal.ppat.1003265. Epub 2013 Mar 28. PLoS Pathog. 2013. PMID: 23555265 Free PMC article.
Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response.
Rajsbaum R, Versteeg GA, Schmid S, Maestre AM, Belicha-Villanueva A, Martínez-Romero C, Patel JR, Morrison J, Pisanelli G, Miorin L, Laurent-Rolle M, Moulton HM, Stein DA, Fernandez-Sesma A, tenOever BR, García-Sastre A. Rajsbaum R, et al. Immunity. 2014 Jun 19;40(6):880-95. doi: 10.1016/j.immuni.2014.04.018. Epub 2014 May 29. Immunity. 2014. PMID: 24882218 Free PMC article.
56 results