Chen CH - Search Results

1

A feedforward circuit between KLF5 and lncRNA KPRT4 contributes to basal-like breast cancer.

Du G, Sun J, Li Z, Zhang Q, Liu W, Yang C, Zhao P, Wang X, Yin Q, Luo Y, Song J, Wen Y, Wang H, Chen CH, Hu G, Zhou Z, Mao X, Liu W, Liu Z, Jiang D, Chen C. Du G, et al. Among authors: chen ch, chen c. Cancer Lett. 2022 May 28;534:215618. doi: 10.1016/j.canlet.2022.215618. Epub 2022 Mar 6. Cancer Lett. 2022. PMID: 35259457

2

Inhibition of super enhancer downregulates the expression of KLF5 in basal-like breast cancers.

Chen CH, Yang N, Zhang Y, Ding J, Zhang W, Liu R, Liu W, Chen C. Chen CH, et al. Among authors: chen c. Int J Biol Sci. 2019 Jun 10;15(8):1733-1742. doi: 10.7150/ijbs.35138. eCollection 2019. Int J Biol Sci. 2019. PMID: 31360115 Free PMC article.

3

Mifepristone Derivative FZU-00,003 Suppresses Triple-negative Breast Cancer Cell Growth partially via miR-153-KLF5 axis.

Liu R, Chen H, Zhao P, Chen CH, Liang H, Yang C, Zhou Z, Zhi X, Liu S, Chen C. Liu R, et al. Among authors: chen ch, chen c, chen h. Int J Biol Sci. 2020 Jan 1;16(4):611-619. doi: 10.7150/ijbs.39491. eCollection 2020. Int J Biol Sci. 2020. PMID: 32025209 Free PMC article.

4

Arginine methyltransferase PRMT5 methylates and stabilizes KLF5 via decreasing its phosphorylation and ubiquitination to promote basal-like breast cancer.

Wang X, Qiu T, Wu Y, Yang C, Li Y, Du G, He Y, Liu W, Liu R, Chen CH, Shi Y, Pan J, Zhou J, Jiang D, Chen C. Wang X, et al. Among authors: chen ch, chen c. Cell Death Differ. 2021 Oct;28(10):2931-2945. doi: 10.1038/s41418-021-00793-0. Epub 2021 May 10. Cell Death Differ. 2021. PMID: 33972717 Free PMC article.

5

KLF5-induced lncRNA IGFL2-AS1 promotes basal-like breast cancer cell growth and survival by upregulating the expression of IGFL1.

Wang H, Shi Y, Chen CH, Wen Y, Zhou Z, Yang C, Sun J, Du G, Wu J, Mao X, Liu R, Chen C. Wang H, et al. Among authors: chen ch, chen c. Cancer Lett. 2021 Sep 1;515:49-62. doi: 10.1016/j.canlet.2021.04.016. Epub 2021 May 27. Cancer Lett. 2021. PMID: 34052325

6

YB-1 is a positive regulator of KLF5 transcription factor in basal-like breast cancer.

Jiang D, Qiu T, Peng J, Li S, Tala, Ren W, Yang C, Wen Y, Chen CH, Sun J, Wu Y, Liu R, Zhou J, Wu K, Liu W, Mao X, Zhou Z, Chen C. Jiang D, et al. Among authors: chen ch, chen c. Cell Death Differ. 2022 Jun;29(6):1283-1295. doi: 10.1038/s41418-021-00920-x. Epub 2022 Jan 13. Cell Death Differ. 2022. PMID: 35022570 Free PMC article.

7

Poly(ADP-ribose)polymerase (PARP) inhibition and anticancer activity of simmiparib, a new inhibitor undergoing clinical trials.

Yuan B, Ye N, Song SS, Wang YT, Song Z, Chen HD, Chen CH, Huan XJ, Wang YQ, Su Y, Shen YY, Sun YM, Yang XY, Chen Y, Guo SY, Gan Y, Gao ZW, Chen XY, Ding J, He JX, Zhang A, Miao ZH. Yuan B, et al. Among authors: chen xy, chen ch, chen hd, chen y. Cancer Lett. 2017 Feb 1;386:47-56. doi: 10.1016/j.canlet.2016.11.010. Epub 2016 Nov 12. Cancer Lett. 2017. PMID: 27847302

8

Increased PARP1-DNA binding due to autoPARylation inhibition of PARP1 on DNA rather than PARP1-DNA trapping is correlated with PARP1 inhibitor's cytotoxicity.

Chen HD, Chen CH, Wang YT, Guo N, Tian YN, Huan XJ, Song SS, He JX, Miao ZH. Chen HD, et al. Among authors: chen ch. Int J Cancer. 2019 Aug 1;145(3):714-727. doi: 10.1002/ijc.32131. Epub 2019 Jan 30. Int J Cancer. 2019. PMID: 30675909

9

Discovery of heterocyclic substituted dihydropyrazoles as potent anticancer agents.

Chen CH, Jiang Y, Wu R, Tang Y, Wan C, Gao H, Mao Z. Chen CH, et al. Bioorg Med Chem Lett. 2021 Sep 15;48:128233. doi: 10.1016/j.bmcl.2021.128233. Epub 2021 Jun 29. Bioorg Med Chem Lett. 2021. PMID: 34214509

10

Development of actein derivatives as potent anti-triple negative breast cancer agents.

Zhang H, Chen Y, Huang S, Xiao WW, Qiu MH, Shao LD, Chen CH, Li D. Zhang H, et al. Among authors: chen ch, chen y. Bioorg Med Chem Lett. 2023 Jun 1;89:129307. doi: 10.1016/j.bmcl.2023.129307. Epub 2023 Apr 28. Bioorg Med Chem Lett. 2023. PMID: 37121522

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