Lin H - Search Results

1

Long-chain fatty acyl coenzyme A inhibits NME1/2 and regulates cancer metastasis.

Zhang S, Nelson OD, Price IR, Zhu C, Lu X, Fernandez IR, Weiss RS, Lin H. Zhang S, et al. Among authors: lin h. Proc Natl Acad Sci U S A. 2022 Mar 15;119(11):e2117013119. doi: 10.1073/pnas.2117013119. Epub 2022 Mar 8. Proc Natl Acad Sci U S A. 2022. PMID: 35259022 Free PMC article.

2

SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine.

Jiang H, Khan S, Wang Y, Charron G, He B, Sebastian C, Du J, Kim R, Ge E, Mostoslavsky R, Hang HC, Hao Q, Lin H. Jiang H, et al. Among authors: lin h. Nature. 2013 Apr 4;496(7443):110-3. doi: 10.1038/nature12038. Nature. 2013. PMID: 23552949 Free PMC article.

3

Identification of proteins capable of metal reduction from the proteome of the Gram-positive bacterium Desulfotomaculum reducens MI-1 using an NADH-based activity assay.

Otwell AE, Sherwood RW, Zhang S, Nelson OD, Li Z, Lin H, Callister SJ, Richardson RE. Otwell AE, et al. Among authors: lin h. Environ Microbiol. 2015 Jun;17(6):1977-90. doi: 10.1111/1462-2920.12673. Epub 2015 Jan 27. Environ Microbiol. 2015. PMID: 25389064 Free PMC article.

4

Molecular dissection of a putative iron reductase from Desulfotomaculum reducens MI-1.

Li Z, Kim DD, Nelson OD, Otwell AE, Richardson RE, Callister SJ, Lin H. Li Z, et al. Among authors: lin h. Biochem Biophys Res Commun. 2015 Nov 20;467(3):503-8. doi: 10.1016/j.bbrc.2015.10.016. Epub 2015 Oct 8. Biochem Biophys Res Commun. 2015. PMID: 26454174 Free PMC article.

5

A SIRT2-Selective Inhibitor Promotes c-Myc Oncoprotein Degradation and Exhibits Broad Anticancer Activity.

Jing H, Hu J, He B, Negrón Abril YL, Stupinski J, Weiser K, Carbonaro M, Chiang YL, Southard T, Giannakakou P, Weiss RS, Lin H. Jing H, et al. Among authors: lin h. Cancer Cell. 2016 Mar 14;29(3):297-310. doi: 10.1016/j.ccell.2016.02.007. Cancer Cell. 2016. PMID: 26977881 Free PMC article.

6

Metabolomics-assisted proteomics identifies succinylation and SIRT5 as important regulators of cardiac function.

Sadhukhan S, Liu X, Ryu D, Nelson OD, Stupinski JA, Li Z, Chen W, Zhang S, Weiss RS, Locasale JW, Auwerx J, Lin H. Sadhukhan S, et al. Among authors: lin h. Proc Natl Acad Sci U S A. 2016 Apr 19;113(16):4320-5. doi: 10.1073/pnas.1519858113. Epub 2016 Apr 5. Proc Natl Acad Sci U S A. 2016. PMID: 27051063 Free PMC article.

7

SIRT6 regulates Ras-related protein R-Ras2 by lysine defatty-acylation.

Zhang X, Spiegelman NA, Nelson OD, Jing H, Lin H. Zhang X, et al. Among authors: lin h. Elife. 2017 Apr 13;6:e25158. doi: 10.7554/eLife.25158. Elife. 2017. PMID: 28406396 Free PMC article.

8

Direct Comparison of SIRT2 Inhibitors: Potency, Specificity, Activity-Dependent Inhibition, and On-Target Anticancer Activities.

Spiegelman NA, Price IR, Jing H, Wang M, Yang M, Cao J, Hong JY, Zhang X, Aramsangtienchai P, Sadhukhan S, Lin H. Spiegelman NA, et al. Among authors: lin h. ChemMedChem. 2018 Sep 19;13(18):1890-1894. doi: 10.1002/cmdc.201800391. Epub 2018 Aug 13. ChemMedChem. 2018. PMID: 30058233 Free PMC article.

9

A Small-Molecule SIRT2 Inhibitor That Promotes K-Ras4a Lysine Fatty-Acylation.

Spiegelman NA, Hong JY, Hu J, Jing H, Wang M, Price IR, Cao J, Yang M, Zhang X, Lin H. Spiegelman NA, et al. Among authors: lin h. ChemMedChem. 2019 Apr 3;14(7):744-748. doi: 10.1002/cmdc.201800715. Epub 2019 Feb 25. ChemMedChem. 2019. PMID: 30734528 Free PMC article.

10

Novel Lysine-Based Thioureas as Mechanism-Based Inhibitors of Sirtuin 2 (SIRT2) with Anticancer Activity in a Colorectal Cancer Murine Model.

Farooqi AS, Hong JY, Cao J, Lu X, Price IR, Zhao Q, Kosciuk T, Yang M, Bai JJ, Lin H. Farooqi AS, et al. Among authors: lin h. J Med Chem. 2019 Apr 25;62(8):4131-4141. doi: 10.1021/acs.jmedchem.9b00191. Epub 2019 Apr 15. J Med Chem. 2019. PMID: 30986062 Free PMC article.

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