Caron MG - Search Results

1

Discovery of a functionally selective ghrelin receptor (GHSR_1a) ligand for modulating brain dopamine.

Gross JD, Kim DW, Zhou Y, Jansen D, Slosky LM, Clark NB, Ray CR, Hu X, Southall N, Wang A, Xu X, Barnaeva E, Wetsel WC, Ferrer M, Marugan JJ, Caron MG, Barak LS, Toth K. Gross JD, et al. Among authors: caron mg. Proc Natl Acad Sci U S A. 2022 Mar 8;119(10):e2112397119. doi: 10.1073/pnas.2112397119. Epub 2022 Mar 3. Proc Natl Acad Sci U S A. 2022. PMID: 35239443 Free PMC article.

2

G Protein and β-arrestin signaling bias at the ghrelin receptor.

Evron T, Peterson SM, Urs NM, Bai Y, Rochelle LK, Caron MG, Barak LS. Evron T, et al. Among authors: caron mg. J Biol Chem. 2014 Nov 28;289(48):33442-55. doi: 10.1074/jbc.M114.581397. Epub 2014 Sep 26. J Biol Chem. 2014. PMID: 25261469 Free PMC article.

3

Ghrelin receptor antagonism of hyperlocomotion in cocaine-sensitized mice requires βarrestin-2.

Toth K, Slosky LM, Pack TF, Urs NM, Boone P, Mao L, Abraham D, Caron MG, Barak LS. Toth K, et al. Among authors: caron mg. Synapse. 2018 Jan;72(1):10.1002/syn.22012. doi: 10.1002/syn.22012. Epub 2017 Oct 7. Synapse. 2018. PMID: 28941296 Free PMC article.

4

Designing Functionally Selective Noncatechol Dopamine D₁ Receptor Agonists with Potent In Vivo Antiparkinsonian Activity.

Martini ML, Ray C, Yu X, Liu J, Pogorelov VM, Wetsel WC, Huang XP, McCorvy JD, Caron MG, Jin J. Martini ML, et al. Among authors: caron mg. ACS Chem Neurosci. 2019 Sep 18;10(9):4160-4182. doi: 10.1021/acschemneuro.9b00410. Epub 2019 Aug 20. ACS Chem Neurosci. 2019. PMID: 31387346 Free PMC article.

5

Encoding the β-Arrestin Trafficking Fate of Ghrelin Receptor GHSR1a: C-Tail-Independent Molecular Determinants in GPCRs.

Toth K, Nagi K, Slosky LM, Rochelle L, Ray C, Kaur S, Shenoy SK, Caron MG, Barak LS. Toth K, et al. Among authors: caron mg. ACS Pharmacol Transl Sci. 2019 Jun 3;2(4):230-246. doi: 10.1021/acsptsci.9b00018. eCollection 2019 Aug 9. ACS Pharmacol Transl Sci. 2019. PMID: 32259059 Free PMC article.

6

Biased Allosteric Modulators: New Frontiers in GPCR Drug Discovery.

Slosky LM, Caron MG, Barak LS. Slosky LM, et al. Among authors: caron mg. Trends Pharmacol Sci. 2021 Apr;42(4):283-299. doi: 10.1016/j.tips.2020.12.005. Epub 2021 Feb 10. Trends Pharmacol Sci. 2021. PMID: 33581873 Free PMC article. Review.

7

G-protein-coupled receptor regulation: role of G-protein-coupled receptor kinases and arrestins.

Ferguson SS, Barak LS, Zhang J, Caron MG. Ferguson SS, et al. Among authors: caron mg. Can J Physiol Pharmacol. 1996 Oct;74(10):1095-110. doi: 10.1139/cjpp-74-10-1095. Can J Physiol Pharmacol. 1996. PMID: 9022829 Review.

8

Role for G protein-coupled receptor kinase in agonist-specific regulation of mu-opioid receptor responsiveness.

Zhang J, Ferguson SS, Barak LS, Bodduluri SR, Laporte SA, Law PY, Caron MG. Zhang J, et al. Among authors: caron mg. Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):7157-62. doi: 10.1073/pnas.95.12.7157. Proc Natl Acad Sci U S A. 1998. PMID: 9618555 Free PMC article.

9

The beta2-adrenergic receptor/betaarrestin complex recruits the clathrin adaptor AP-2 during endocytosis.

Laporte SA, Oakley RH, Zhang J, Holt JA, Ferguson SS, Caron MG, Barak LS. Laporte SA, et al. Among authors: caron mg. Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3712-7. doi: 10.1073/pnas.96.7.3712. Proc Natl Acad Sci U S A. 1999. PMID: 10097102 Free PMC article.

10

Constitutive arrestin-mediated desensitization of a human vasopressin receptor mutant associated with nephrogenic diabetes insipidus.

Barak LS, Oakley RH, Laporte SA, Caron MG. Barak LS, et al. Among authors: caron mg. Proc Natl Acad Sci U S A. 2001 Jan 2;98(1):93-8. doi: 10.1073/pnas.98.1.93. Proc Natl Acad Sci U S A. 2001. PMID: 11134505 Free PMC article.

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