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The FDA-Approved Drug Cobicistat Synergizes with Remdesivir To Inhibit SARS-CoV-2 Replication In Vitro and Decreases Viral Titers and Disease Progression in Syrian Hamsters.
Shytaj IL, Fares M, Gallucci L, Lucic B, Tolba MM, Zimmermann L, Adler JM, Xing N, Bushe J, Gruber AD, Ambiel I, Taha Ayoub A, Cortese M, Neufeldt CJ, Stolp B, Sobhy MH, Fathy M, Zhao M, Laketa V, Diaz RS, Sutton RE, Chlanda P, Boulant S, Bartenschlager R, Stanifer ML, Fackler OT, Trimpert J, Savarino A, Lusic M. Shytaj IL, et al. Among authors: lucic b. mBio. 2022 Apr 26;13(2):e0370521. doi: 10.1128/mbio.03705-21. Epub 2022 Mar 1. mBio. 2022. PMID: 35229634 Free PMC article.
Alterations of redox and iron metabolism accompany the development of HIV latency.
Shytaj IL, Lucic B, Forcato M, Penzo C, Billingsley J, Laketa V, Bosinger S, Stanic M, Gregoretti F, Antonelli L, Oliva G, Frese CK, Trifunovic A, Galy B, Eibl C, Silvestri G, Bicciato S, Savarino A, Lusic M. Shytaj IL, et al. Among authors: lucic b. EMBO J. 2020 May 4;39(9):e102209. doi: 10.15252/embj.2019102209. Epub 2020 Mar 11. EMBO J. 2020. PMID: 32157726 Free PMC article.
Microscopy-based assay for semi-quantitative detection of SARS-CoV-2 specific antibodies in human sera: A semi-quantitative, high throughput, microscopy-based assay expands existing approaches to measure SARS-CoV-2 specific antibody levels in human sera.
Pape C, Remme R, Wolny A, Olberg S, Wolf S, Cerrone L, Cortese M, Klaus S, Lucic B, Ullrich S, Anders-Össwein M, Wolf S, Cerikan B, Neufeldt CJ, Ganter M, Schnitzler P, Merle U, Lusic M, Boulant S, Stanifer M, Bartenschlager R, Hamprecht FA, Kreshuk A, Tischer C, Kräusslich HG, Müller B, Laketa V. Pape C, et al. Among authors: lucic b. Bioessays. 2021 Mar;43(3):e2000257. doi: 10.1002/bies.202000257. Epub 2020 Dec 30. Bioessays. 2021. PMID: 33377226 Free PMC article.
Viruses in the Nucleus.
Lucic B, de Castro IJ, Lusic M. Lucic B, et al. Cold Spring Harb Perspect Biol. 2021 Aug 2;13(8):a039446. doi: 10.1101/cshperspect.a039446. Cold Spring Harb Perspect Biol. 2021. PMID: 33753405 Free PMC article. Review.
Glycolysis downregulation is a hallmark of HIV-1 latency and sensitizes infected cells to oxidative stress.
Shytaj IL, Procopio FA, Tarek M, Carlon-Andres I, Tang HY, Goldman AR, Munshi M, Kumar Pal V, Forcato M, Sreeram S, Leskov K, Ye F, Lucic B, Cruz N, Ndhlovu LC, Bicciato S, Padilla-Parra S, Diaz RS, Singh A, Lusic M, Karn J, Alvarez-Carbonell D, Savarino A. Shytaj IL, et al. Among authors: lucic b. EMBO Mol Med. 2021 Aug 9;13(8):e13901. doi: 10.15252/emmm.202013901. Epub 2021 Jul 20. EMBO Mol Med. 2021. PMID: 34289240 Free PMC article.
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